Key TakeawaysHPV vaccination may reduce pregnancy complicationsWomen vaccinated against HPV had lower risks of preterm birth, early rupture of the amniotic sac and having a very small babyWomen vaccinated before age 17 showed stronger benefits.THURSDAY, Oct. 8, 2026 (HealthDay News) — The HPV vaccine is best known for protecting against cervical cancer.But, it may have another major benefit: reducing the risk of serious pregnancy complications.A team led by Zhongsong Zhang, of the Karolinska Institute in Stockholm, conducted a large study that looked at more than 624,000 first-time births.About 93,000 of the women had been vaccinated against human papillomavirus, HPV — a common, sexually transmitted infection that can cause precancerous and cancerous changes.Those who were vaccinated had lower odds of several complications, including preterm and very preterm birth, the amniotic sac rupturing too early, and having a severely small baby.The link was generally stronger among women vaccinated before age 17. They had about 10% lower odds of preterm birth and 11% lower odds of spontaneous preterm birth.Researchers said vaccination may help by preventing HPV infection and reducing the need for procedures to remove abnormal cervical tissue. These procedures have been linked to a higher risk of preterm birth.Because this was an observational study, it can't prove cause and effect.But researchers say the study's large size, high-quality data and long follow-up strengthen the findings."Our results suggest that human papillomavirus vaccination is not only safe with respect to pregnancy outcomes but may also confer additional benefits by reducing the risk of adverse events," they said in a news release.The findings were published Oct. 7 in The BMJ.More informationThe Cleveland Clinic has more on the human papillomavirus.SOURCE: HealthDay TV, Oct. 8, 2026 .What This Means For YouThe HPV vaccine may not only protect against cervical cancer but also reduce the risk of serious pregnancy complications, especially when given at a younger age..Sign up for our weekly HealthDay newsletter