Most people taking antidepressants do not suffer severe withdrawal when they stop their medication, according to a large, new study.Researchers found the majority of patients experience one new symptom, the most common being dizziness, nausea, vertigo and nervousness.The lead author says, “Importantly, depression relapse was not linked to antidepressant withdrawal in these studies…” and was more likely to reflect illness recurrence.The researchers analyzed 50 clinical trials involving more than 17,800 adult patients. The data involved different types of antidepressants, including popular SSRIs (Selective Serotonin Reuptake Inhibitors) and SNRIs (Serotonin-Norepinephrine Reuptake Inhibitors).While the nature and rates of different symptoms varied between antidepressants, overall, the number of new symptoms after discontinuation was generally one. And experiencing just one symptom is below the four or more cutoff for clinically important withdrawal, according to the researchers.The authors note while uncommon, there could be a sub-group of people who develop more severe withdrawal symptoms than the wider population of antidepressant users.Source: JAMA PsychiatryAuthor Affiliations: Imperial College London, King’s College London.Sign up for our weekly HealthDay newsletter