WEDNESDAY, March 29 (HealthDay News) -- A case report in the March issue of Urology describes a rarity: a metachronous solitary metastasis of renal cell carcinoma (RCC) to the prostate, presenting nine years after radical nephrectomy.
The case is that of a 59-year-old man with a history of left RCC treated by nephrectomy. Nearly nine years later, the man presented with gross hematuria and severe symptoms of the lower urinary tract with bladder outlet obstruction. Rectal examination revealed an enlarged prostate. The prostate-specific antigen level was 2.0 ng/ml.
Alejandro Rodriguez, M.D., and colleagues at the University of South Florida, Tampa, performed a transurethral resection of the prostate. Pathology revealed metastatic RCC. Three months later, the physicians performed radical prostatectomy without complications. Surgical margins were clear. Six months after surgery, the patient had no evidence of disease recurrence, and his prostate-specific antigen level was 0.01 ng/ml.
"Although delayed metastases from RCC of up to 25 years have been reported, ours is only the second case of delayed metastasis to the prostate detected in a living patient," the authors said. "Our case illustrates the propensity of RCC for unpredictable presentations, as well as unusual late sites of metastases."
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