The American Heart Association's International Stroke Conference
The American Heart Association's annual International Stroke Conference was held from Feb. 12 to 14 in San Diego and attracted nearly 4,000 participants from around the world, including cerebrovascular research and practice experts. The conference featured more than 1,500 presentations that emphasized basic, clinical, and translational medicine as well as providing insight into the prevention, management, and treatment of strokes.
In one study, Richard Bernstein, M.D., of the Northwestern University Feinberg School of Medicine in Chicago, and colleagues found that using an implantable cardiac monitor, the Reveal XT, improved the detection of atrial fibrillation (AF) after an ischemic stroke of unknown cause.
"Detecting AF prompts a change in medical therapy from aspirin-like drugs to anticoagulant drugs, which are more effective at preventing strokes in patients with AF," said Bernstein. "By three years, the implantable device found that 30 percent of the patients had AF, whereas we only found 3 percent of patients with AF using standard cardiac monitoring techniques."
Several authors disclosed financial ties to Medtronic, the manufacturer of the Reveal XT.
In another study, Devin Brown, M.D., of the University of Michigan in Ann Arbor, and colleagues found that stroke patients whose stroke-related injury is located in the brainstem have a higher prevalence of sleep apnea than those with stroke-related injury elsewhere in the brain.
"Similarly, brainstem location of stroke-related injury was also linked to severity of sleep apnea," said Brown. "Clinicians should have a high suspicion for sleep apnea in any ischemic stroke patient, but even more so in those with brainstem stroke. However, because no definitive study has proven the benefits of sleep apnea treatment with respect to stroke outcomes, routine sleep apnea screening is not yet part of guidelines."
Several authors disclosed financial ties to the pharmaceutical and medical device industries.
Gregg Fonarow, M.D., of the University of California in Los Angeles, and colleagues examined data from hospitals that have adopted Target: Stroke, the American Heart Association/American Stroke Association's national quality initiative. The primary aim of Target: Stroke is to increase the number of stroke patients treated with tissue plasminogen activator (tPA) for acute ischemic stroke within 60 minutes of hospital arrival.
"The study demonstrated that patients received stroke therapy significantly faster in hospitals that participated in Target: Stroke," said Fonarow. "Between 2010 and 2013, the time between hospital arrival and use of tPA (door-to-needle time) dropped by 15 minutes, from 74 to 59 minutes, in hospitals that participated in Target: Stroke."
This study also found that the percentage of patients treated within the recommended timeframe increased from less than one-third before Target: Stroke to more than half afterwards.
"The Target: Stroke program goal of 50 percent or more patients having door-to-needle times within 60 minutes was successfully achieved. Faster treatment was associated with improved patient outcomes and fewer complications, including death," said Fonarow. "These findings further reinforce the importance and clinical benefits of faster administration of intravenous tPA. By showing that the timeliness of tPA administration can be improved at the national level, these findings also support further expansion of the Target: Stroke initiative."
Several authors disclosed financial ties to the pharmaceutical and medical device industries.
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