PREVENT Risk Score Accurately IDs People With Coronary Artery Calcium

WEDNESDAY, May 21, 2025 (HealthDay News) -- The 2023 Predicting Risk of Cardiovascular Disease Events (PREVENT) risk score accurately identifies individuals with coronary artery calcium (CAC), according to a research letter published online May 21 in the Journal of the American Heart Association.Aaron J. Rhee, M.D., from New York University in New York City, and colleagues queried electronic health records to compare PREVENT risk scores with subclinical coronary atherosclerosis, detected through scoring of CAC deposits on coronary computed tomography angiography.A total of 6,961 patients had no missing PREVENT inputs. The researchers found that PREVENT risk was 20 percent in 43.6, 15.8, 34.4, and 6.2 percent, respectively, with median CAC of 0, 0, 19, and 101, for each category. The Spearman correlation was 0.47 between PREVENT and CAC scores. Among those with PREVENT score 100 (areas under the receiver operating characteristic curve, 0.755 and 0.761, respectively). Risk discrimination of incident myocardial infarction events was significantly improved by adding CAC to PREVENT risk (change in c-statistic, 0.014); the reverse was true but not statistically significant."The findings illustrate that PREVENT is accurate in identifying people who may have subclinical risk for cardiovascular disease, meaning blocked arteries before symptoms develop," coauthor Morgan E. Grams, M.D, Ph.D., also from New York University, said in a statement.One author disclosed ties to Heartflow and Abbott Vascular.Abstract/Full Text.Sign up for our weekly HealthDay newsletter