Here are what the editors at HealthDay consider to be the most important developments in Nursing for May 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Slow-Growing Melanomas Lose Structure, Vary Color With Time
THURSDAY, May 31 (HealthDay News) -- The diameter of most slow-growing melanomas (SGMs) changes very little over time, but the lesions can become more disorganized, less structured, and change or develop new colors, according to a study published in the June issue of the British Journal of Dermatology.
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Infants May Be Exposed to Phthalates From PVC Floors
THURSDAY, May 31 (HealthDay News) -- Soft polyvinyl chloride (PVC) flooring material in an infant's bedroom, the infant's body surface area, and the use of infant formula are associated with an infant's increased uptake of phthalates, which may be linked to several chronic childhood diseases, according to research published online May 7 in Indoor Air.
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Adjunct Zinc Cuts Antibiotic Treatment Failure for Infants
THURSDAY, May 31 (HealthDay News) -- For infants aged 7 to 120 days with probable serious bacterial infection, zinc given as an adjunct to standard antibiotic treatment is associated with less treatment failure, according to a study published online May 31 in The Lancet.
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White Matter Integrity Linked to Intelligence in Elderly
THURSDAY, May 31 (HealthDay News) -- Differences in white matter integrity in the brain account for some of the variation in general intelligence in elderly individuals, with their effect mediated by information-processing speed, according to a study published online May 22 in Molecular Psychiatry.
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BMI Thresholds for Gestational Diabetes Differ by Race
THURSDAY, May 31 (HealthDay News) -- There is considerable racial/ethnic variation in the prevalence of gestational diabetes mellitus (GDM) by body mass index (BMI), according to a study published online May 22 in Diabetes Care.
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Patient Goals for Presenting Internet Research to Docs Vary
THURSDAY, May 31 (HealthDay News) -- When cancer patients approach their doctors with Internet research regarding their disease, their goals for the conversation affect how they perceive their provider's responses (attributions), according to a study published online May 17 in the Journal of Applied Communication Research.
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Radiation Ups Event-Free, Not Overall Survival in Ped Hodgkin's
THURSDAY, May 31 (HealthDay News) -- For children with Hodgkin's lymphoma who respond to chemotherapy, treatment with low-dose involved-field radiation therapy (IFRT) improves event-free survival (EFS), but has no significant impact on overall survival (OS), in long-term follow-up, according to a study published online May 29 in the Journal of Clinical Oncology.
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Neural Link Between Resiliency and Alcohol, Drug Use Identified
THURSDAY, May 31 (HealthDay News) -- For young adults, the coupling strength between the subthalamic nucleus (STN) and median cingulate cortex may be involved in the association between resiliency and alcohol/drug use, according to a study published online May 15 in Alcoholism: Clinical & Experimental Research.
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Intensive Glucose Control Helps Surrogate Renal End Points
THURSDAY, May 31 (HealthDay News) -- Intensive glucose therapy significantly reduces microalbuminuria and macroalbuminuria in adults with type 2 diabetes, but does not improve clinical renal outcomes, according to a study published in the May 28 issue of the Archives of Internal Medicine.
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Cardiovascular Risk Counseling Improves Statin Adherence
THURSDAY, May 31 (HealthDay News) -- For patients taking statins for prevention of cardiovascular disease (CVD), extended care with nurse-led cardiovascular risk-factor counseling improves statin adherence and reduces anxiety, with improvements seen in low-density lipoprotein cholesterol for primary prevention patients, according to a study published online May 24 in The American Journal of Cardiology.
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Repeat CT Scan Urged for Head Trauma Patients on Warfarin
WEDNESDAY, May 30 (HealthDay News) -- Minor head trauma patients taking warfarin should have a repeat computed tomography (CT) scan prior to discharge to detect delayed hemorrhage, particularly in those with an initial international normalized ratio (INR) higher than 3, according to research published in the June issue of the Annals of Emergency Medicine.
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Hypothermia of Some Benefit to Neonates With Encephalopathy
WEDNESDAY, May 30 (HealthDay News) -- For infants with neonatal hypoxic-ischemic encephalopathy, undergoing whole-body hypothermia results in lower mortality rates as well as a nonsignificant reduction in the combined end point of death or an IQ score of less than 70 at age 6 to 7 years, compared with usual care, according to a study published in the May 31 issue of the New England Journal of Medicine.
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Oral, Injected Methotrexate Have Similar Efficacy in JIA
WEDNESDAY, May 30 (HealthDay News) -- Oral and injected methotrexate are equally effective for treating children with juvenile idiopathic arthritis, according to a study published online May 30 in Arthritis Care & Research.
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Link Between Obesity and Lower-Extremity Lymphedema Explored
WEDNESDAY, May 30 (HealthDay News) -- Lower-extremity lymphedema may be due to extreme obesity, as there appears to be a body mass index (BMI) threshold above which lymphatic flow becomes impaired, according to a letter to the editor published in the May 31 issue of the New England Journal of Medicine.
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Online Adderall May Contain Wrong Active Ingredients
WEDNESDAY, May 30 (HealthDay News) -- Consumers purchasing the drug Adderall online may be buying a counterfeit version that could be ineffective, unsafe, and potentially harmful, according to a safety alert issued May 30 by the U.S. Food and Drug Administration.
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Working Night Shift May Increase Breast Cancer Risk
WEDNESDAY, May 30 (HealthDay News) -- There may be an increased risk of developing breast cancer among women who work night shifts, according to a study published online May 29 in Occupational & Environmental Medicine.
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Protein Elevated in Stroke Patients With Microbleeds
WEDNESDAY, May 30 (HealthDay News) -- Serum levels of vascular endothelial growth factor (VEGF), a marker of vascular permeability, are significantly higher in stroke patients with cerebral microbleeds, according to a study published online May 28 in the Archives of Neurology.
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Risk Models Only Slightly Up Prediction of Complex Diseases
WEDNESDAY, May 30 (HealthDay News) -- Risk models that take gene-gene and gene-environment interactions into account only slightly improve the prediction of risk for three complex diseases, according to a study published online May 24 in the American Journal of Human Genetics.
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Acne Medication Isotretinoin Increases Risk of Eye Disorders
WEDNESDAY, May 30 (HealthDay News) -- The acne medicine isotretinoin may be linked to a nearly two-fold increased risk of ocular adverse effects in users, according to a study published online April 16 in the Archives of Dermatology.
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Post-Transplant, eGFR Impacts Cardio Risk Independently
WEDNESDAY, May 30 (HealthDay News) -- In stable kidney transplant recipients, kidney function, as determined by estimated glomerular filtration rate (eGFR), is independently associated with cardiovascular (CVD) events and death, according to research published online May 17 in the American Journal of Transplantation.
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Glucose Levels at Admission Predict Death in Pneumonia
WEDNESDAY, May 30 (HealthDay News) -- For patients with community-acquired pneumonia without preexisting diabetes, serum glucose levels at admission are predictive of death at 28 and 90 days, according to a study published online May 29 in BMJ.
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Pathologic Response Prediction of Survival Aided by Tumor Type
WEDNESDAY, May 30 (HealthDay News) -- Pathologic complete response (pCR) is more highly predictive of recurrence-free survival (RFS) when specific breast cancer tumor type is factored in, according to a study published online May 29 in the Journal of Clinical Oncology.
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Mobile Technology Helps Improve Lifestyle Coaching
WEDNESDAY, May 30 (HealthDay News) -- Coaching supported by mobile technology can help adults improve their lifestyle, most significantly through increasing their intake of fruits and vegetables and decreasing sedentary leisure time, according to a study published in the May 28 issue of the Archives of Internal Medicine.
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Diabetes Linked to Lung Cancer in Postmenopausal Women
WEDNESDAY, May 30 (HealthDay News) -- Postmenopausal women with diabetes are at a significantly higher risk of developing lung cancer, particularly if they require insulin therapy, according to research published online May 22 in Diabetes Care.
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AHA Recommends More Safeguards for Genetic Testing
TUESDAY, May 29 (HealthDay News) -- While genetics show promise for improving health, more safeguards are needed to protect patients and allow scientific and clinical research to continue, according to recommendations issued by the American Heart Association and published online May 29 in Circulation.
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NSAID Use Linked to Reduced Risk of Skin Cancer
TUESDAY, May 29 (HealthDay News) -- Nonsteroidal anti-inflammatory drugs (NSAIDs), including nonselective NSAIDs and older cyclooxygenase (COX)-2 inhibitors, are associated with a decreased risk of squamous cell carcinoma (SCC) and malignant melanoma (MM), particularly among long-term and high-intensity NSAID users, according to a study published online May 29 in Cancer.
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Lower Limb Muscle Limitations Hamper Walking in Diabetes
TUESDAY, May 29 (HealthDay News) -- In older adults, diabetes correlates with slower walking speed, and diabetes-linked reductions in muscle strength and worse muscle quality contribute to these walking limitations, according to a study published online May 17 in Diabetes Care.
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School-Based Exercise Program Improves Bone Mass, Size
TUESDAY, May 29 (HealthDay News) -- A long-term, school-based exercise program for children is associated with increased bone mass and size, with no increase in the fracture risk, according to a study published online May 28 in Pediatrics.
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Solvent Exposure Tied to Lower Cognition Among Less Educated
TUESDAY, May 29 (HealthDay News) -- Occupational exposure to chemical solvents affects the cognitive abilities of less-educated workers, but not more-educated workers, with a dose-response relationship between lifetime exposure and the risk of poor cognition, according to a study published in the May 29 issue of Neurology.
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AAP Cautions Against Diagnosis of Sensory Processing Disorder
TUESDAY, May 29 (HealthDay News) -- Pediatricians should avoid the use of sensory processing disorder as an independent diagnosis and should integrate sensory-based therapy as one part of a comprehensive treatment plan, according to a policy statement issued by the American Academy of Pediatrics (AAP) published online May 28 in Pediatrics.
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Evidence Updated for Impact of Menopausal Hormone Therapy
TUESDAY, May 29 (HealthDay News) -- An updated review clarifies the impact of menopausal hormone therapy on the risk of chronic conditions, according to research published online May 28 in the Annals of Internal Medicine.
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KATNAL1 Essential for Fertility in Male Mice
TUESDAY, May 29 (HealthDay News) -- Mice who have a loss-of-function mutation in KATNAL1, needed for the maturation of sperm, are infertile, which could have implications for treating male infertility and for the development of non-hormonal male contraceptives, according to a study published online May 24 in PLoS Genetics.
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Fever During Pregnancy Linked to Autism in Offspring
TUESDAY, May 29 (HealthDay News) -- Maternal influenza during pregnancy is not associated with autism spectrum disorder (ASD) or developmental delay (DD), but the odds of ASD and DD are increased for children whose mothers had fever during pregnancy, according to a study published online May 5 in the Journal of Autism and Developmental Disorders.
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Evidence for Prevention of HIV Transmission Reviewed
TUESDAY, May 29 (HealthDay News) -- Evidence-based pharmacologic strategies for prevention of HIV transmission include postexposure prophylaxis, pre-exposure prophylaxis, and early initiation of treatment, according to a review published online May 28 in CMAJ, the journal of the Canadian Medical Association.
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PUFA Formula Supplementation Doesn't Up Infant Cognition
TUESDAY, May 29 (HealthDay News) -- Supplementation of infant formula with long-chain polyunsaturated fatty acids (LCPUFAs) is not associated with improved cognition; and infants fed with milk- or soy protein-based formula have similar cognitive development scores, which are slightly lower than those of breastfed infants, according to two studies published online May 28 in Pediatrics.
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Social Networks Play a Role in Childhood Obesity
TUESDAY, May 29 (HealthDay News) -- Afterschool friendships play a critical role in setting physical activity patterns in children as young as 5 to 12 years, according to a study published online May 28 in Pediatrics.
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Video Games Positively Impact Variety of Health Outcomes
MONDAY, May 28 (HealthDay News) -- Although additional rigorous clinical trials are warranted, the literature suggests that video games can be useful in improving a variety of health outcomes, particularly those in the areas of psychological and physical therapy, according to research published online in the June issue of the American Journal of Preventive Medicine.
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C-Section Linked to Increased Risk of Childhood Obesity
MONDAY, May 28 (HealthDay News) -- Infants delivered by cesarean section have two-fold higher odds of childhood obesity, even after adjusting for variables like maternal body mass index (BMI) and birth weight, according to a study published online May 23 in the Archives of Disease in Childhood.
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Research Offers Insight Into Link Between Metabolism, Epilepsy
FRIDAY, May 25 (HealthDay News) -- In mice, modifications to the BCL-2-associated agonist of cell death (BAD) protein -- a protein that reduces glucose metabolism -- induce an increase in metabolically responsive adenosine triphosphate (ATP)-sensitive potassium (KATP) channels, and resistance to seizures, according to a study published in the May 24 issue of Neuron.
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Transvaginal Mesh Op Restores Pelvic Organ Prolapse at Price
FRIDAY, May 25 (HealthDay News) -- Transvaginal mesh (TVM) procedures are effective for anatomical restoration of pelvic organ prolapse (POP), but patients report a worsening of sexual function following surgery, according to a study published online May 21 in The Journal of Sexual Medicine.
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Probability of Long-Term Glioblastoma Survival Assessed
FRIDAY, May 25 (HealthDay News) -- Although the overall mortality rate of glioblastoma is high, compared with patients newly diagnosed with glioblastoma, those who survive two years or more after diagnosis have a favorable conditional probability of future survival, according to a study published online May 8 in Cancer.
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Family History of Alzheimer's Affects Functional Connectivity
FRIDAY, May 25 (HealthDay News) -- Cognitively normal individuals with a family history of late-onset Alzheimer's disease (AD) may display lower resting state functional connectivity in the default mode network (DMN) of the brain, and this effect is detectable even in those who do not carry the apolipoprotein E (APOE) ε4 allele, according to a study published online May 9 in the Annals of Neurology.
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Individual Variation in Antiviral Response Present at Birth
FRIDAY, May 25 (HealthDay News) -- Congenital variations in innate immunity, which are detectable at birth, might predict an infant's susceptibility to acute respiratory tract illness during the first year of life, according to a study published in the May issue of the Journal of Allergy and Clinical Immunology.
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Interneuron Transplant Treats Neuropathic Pain in Mice
FRIDAY, May 25 (HealthDay News) -- Transplanting embryonic GABAergic interneurons into the spinal cords of mice is highly effective for treating neuropathic pain but not inflammatory pain, according to an experimental study published in the May 24 issue of Neuron.
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Childhood Obesity Linked to Idiopathic Intracranial HTN
FRIDAY, May 25 (HealthDay News) -- Overweight and obese children are at higher risk of developing idiopathic intracranial hypertension (IIH), particularly non-Hispanic white adolescent girls, according to a study published online May 24 in The Journal of Pediatrics.
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Cognitive, Sound-Based Combo Therapy Reduces Tinnitus
FRIDAY, May 25 (HealthDay News) -- A multidisciplinary approach to treating tinnitus that combines cognitive behavior therapy with sound-based tinnitus retraining therapy is significantly more effective than currently available treatments for reducing symptoms in otherwise healthy subjects, according to a study published in the May 26 issue of The Lancet.
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Upping Dietary Calcium Buys No Big Cardiovascular Benefit
FRIDAY, May 25 (HealthDay News) -- Increasing dietary calcium intake might not offer significant cardiovascular benefits, but intake through calcium supplements might raise myocardial infarction (MI) risk, according to a study published online May 23 in Heart.
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Magnesium Not Recommended After Subarachnoid Bleed
FRIDAY, May 25 (HealthDay News) -- For patients with aneurysmal subarachnoid hemorrhage, intravenous magnesium sulfate is no better than placebo for reduction of poor outcome, according to a study published online May 25 in The Lancet to coincide with presentation at the European Stroke Conference, held from May 22 to 25 in Lisbon, Portugal.
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Pancreatectomy OK Without Downstaging From Therapy
FRIDAY, May 25 (HealthDay News) -- Pancreatectomy improves median survival in pancreatic cancer patients even when presurgical neoadjuvant therapy does not lead to radiographic downstaging of tumors, according to a study published online May 17 in Cancer.
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Selenium and/or Vitamin E Do Not Prevent Bladder Cancer
FRIDAY, May 25 (HealthDay News) -- Neither selenium nor vitamin E alone or used in combination appears to prevent bladder cancer in men, according to a study published in the June issue of The Journal of Urology.
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Neck Strength, Cervical Spine Mobility Don't Predict Pain
FRIDAY, May 25 (HealthDay News) -- Neither isometric neck muscle strength nor passive mobility of the cervical spine, two physical capacity parameters found to be associated with neck pain in other studies, predicts later neck pain in pain-free working-age women, according to a study published in the May 20 issue of Spine.
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Common Therapies for Basal Cell Carcinoma Offer Similar Survival
FRIDAY, May 25 (HealthDay News) -- For patients with superficial basal cell carcinoma (sBCC), treatment with imiquimod or photodynamic therapy (PDT) results in similar long-term tumor-free survival, according to a review published online May 21 in the British Journal of Dermatology.
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Peritonitis Ups Odds of Mortality in Peritoneal Dialysis Patients
FRIDAY, May 25 (HealthDay News) -- Among patients who die while on peritoneal dialysis, peritonitis is associated with mortality, with the highest odds for peritonitis in the 30 days before death, according to a study published online May 24 in the Journal of the American Society of Nephrology.
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Low Vitamin D Intake Tied to Risk of Thromboembolic Stroke
THURSDAY, May 24 (HealthDay News) -- In Japanese-American men, low dietary vitamin D intake is associated with an increased risk of all stroke and thromboembolic stroke during a 34-year follow-up period, according to a study published online May 24 in Stroke.
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U.S. Stroke Prevalence Little Changed in Recent Years
THURSDAY, May 24 (HealthDay News) -- The prevalence of stroke in the United States has changed little over the past seven years, and disparities by race/ethnicity, education level, and geographic location still persist, according to a study published in the May 25 issue of the U.S. Centers for Disease Control and Prevention's Morbidity & Mortality Weekly Report.
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Vemurafenib, Dabrafenib Linked to Cutaneous Side Effects
THURSDAY, May 24 (HealthDay News) -- The selective small molecule inhibitors of BRAF, vemurafenib and dabrafenib, are associated with diverse cutaneous side effects, including both malignant and benign growths, when used to treat patients with melanoma with the BRAF V600E mutation, according to research published online May 21 in the Journal of the American Academy of Dermatology.
Emily Y. Chu, M.D., Ph.D., of the Hospital of the University of Pennsylvania in Philadelphia, and colleagues evaluated the cutaneous adverse effects of vemurafenib and dabrafenib in 13 patients being treated for metastatic melanoma and one patient being treated for metastatic thyroid cancer.
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Low-Glucose Suspend Function in Insulin Pumps Deemed Safe
THURSDAY, May 24 (HealthDay News) -- Sensor-augmented pump therapy with a low-glucose suspend (LGS) function appears to be safe for patients with type 1 diabetes, according to a study published online May 14 in Diabetes Care.
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Oncologists Grief at Patient Loss Affects Treatment
THURSDAY, May 24 (HealthDay News) -- Oncologists grieve over dead and dying patients, and this grief can affect both their treatment of other patients and their personal lives, according to a research letter published online May 21 in the Archives of Internal Medicine.
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School-Aged Children With ASD Usually Identified At Age 5
THURSDAY, May 24 (HealthDay News) -- School-aged children with special health care needs (CSHCN) who have an autism spectrum disorder (ASD) are usually identified at age 5, and the majority use one or more services and/or at least one psychotropic medication to meet their developmental needs, according to a May data brief issued by the National Center for Health Statistics (NCHS).
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One-Fifth of Healthy Middle-Aged Men Have Low-Grade Murmur
THURSDAY, May 24 (HealthDay News) -- More than one-fifth of healthy middle-aged men have a low-grade systolic heart murmur that confers a nearly five-fold higher risk of future aortic valve replacement (AVR), according to a study published in the June issue of the Journal of Internal Medicine.
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Extending Care Helps Maintain Long-Term Weight Loss
THURSDAY, May 24 (HealthDay News) -- Extended patient care has a moderate effect on long-term maintenance of weight loss, according to a systematic review and meta-analysis published in the June issue of Obesity Reviews.
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Brentuximab Vedotin Effective in Large-Cell Lymphoma
THURSDAY, May 24 (HealthDay News) -- More than half of patients with relapsed or refractory systemic anaplastic large-cell lymphoma (ALCL) treated with the CD30-directed antibody-drug conjugate brentuximab vedotin achieve a complete remission, according to the results of a phase II study published online May 21 in the Journal of Clinical Oncology.
Barbara Pro, M.D., of the Fox Chase Cancer Center in Philadelphia, and colleagues conducted a prospective study involving 58 patients with systemic ALCL and recurrent disease after at least one previous therapy. Participants received an outpatient infusion of brentuximab vedotin 1.8 mg/kg every three weeks. Overall objective response rate was the primary study end point.
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IUDs, Implants Most Effective for Preventing Pregnancy
WEDNESDAY, May 23 (HealthDay News) -- Long-acting reversible methods of contraception such as intrauterine devices (IUDs) or implants are more effective for preventing unintended pregnancy than oral contraceptive pills, transdermal patches, or contraceptive vaginal rings, regardless of the user's age, according to a study published in the May 24 issue of the New England Journal of Medicine.
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Diabetes-Linked Cardio, All-Cause Mortality Decreasing
WEDNESDAY, May 23 (HealthDay News) -- From 1997 to 2006, there was a significant decrease in the cardiovascular disease (CVD) and all-cause mortality rates for U.S. men and women with diabetes, according to research published in the June issue of Diabetes Care.
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Treatment With rt-PA Within Six Hours of Stroke Beneficial
WEDNESDAY, May 23 (HealthDay News) -- For patients with acute ischemic stroke, treatment with recombinant tissue plasminogen activator (rt-PA) within six hours is associated with improved outcomes, according to two studies published online May 23 in The Lancet to coincide with presentation at the European Stroke Conference, held from May 22 to 25 in Lisbon, Portugal.
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Aspirin Effective in Preventing Thromboembolism Recurrence
WEDNESDAY, May 23 (HealthDay News) -- For patients with unprovoked venous thromboembolism who have completed oral anticoagulant treatment, aspirin effectively prevents recurrence, with no apparent increase in the risk of major bleeding, according to a study published in the May 24 issue of the New England Journal of Medicine.
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New Estimates Up Dementia Rates in Mid-Income Countries
WEDNESDAY, May 23 (HealthDay News) -- Use of 10/66 dementia diagnosis criteria (10/66) results in an increase in the estimated incidence of dementia in middle-income countries, according to a study published online May 23 in The Lancet.
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Imaging Predicts Breast Cancer Response to Chemotherapy
WEDNESDAY, May 23 (HealthDay News) -- For women with breast cancer undergoing neoadjuvant chemotherapy before surgery, measurements taken by magnetic resonance imaging (MRI) predict clinical response better than clinical assessment, according to a study published in the June issue of Radiology.
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Regorafenib Active in Metastatic GI Stromal Tumors
WEDNESDAY, May 23 (HealthDay News) -- Regorafenib, an inhibitor of multiple cancer-associated kinases, is active in patients with metastatic gastrointestinal stromal tumors (GIST) who have failed to respond to imatinib and sunitinib, according to a study published online May 21 in the Journal of Clinical Oncology.
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Genetic Testing Doesn't Up Post-Test Health Care Use
WEDNESDAY, May 23 (HealthDay News) -- Receiving genetic susceptibility testing is associated with an increase in physician visits before testing, but does not impact subsequent health care utilization, according to a study published online May 17 in Genetics in Medicine.
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Patients Can Minimize Injection Pain by Looking Away
WEDNESDAY, May 23 (HealthDay News) -- The intensity of pain and unpleasantness associated with a needle prick is affected not only by previous experiences with needle pricks but also by information given prior to an injection, according to research published in the May issue of Pain.
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Maternal Weight Ups Infant Size More Than Glucose Intolerance
WEDNESDAY, May 23 (HealthDay News) -- For women without gestational diabetes, excess maternal weight gain during pregnancy and body mass index (BMI) before pregnancy are greater predictors of large-for-gestational-age infants than mild glucose intolerance and lipid levels, according to a study published online May 22 in CMAJ, the journal of the Canadian Medical Association.
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Characteristics of STEMI Reperfusion Systems Identified
WEDNESDAY, May 23 (HealthDay News) -- Successful ST-segment elevation myocardial infarction (STEMI) reperfusion systems share common characteristics, and these characteristics can be used to set standards for coordinated care, according to research published online May 22 in Circulation: Cardiovascular Quality and Outcomes.
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Hunter-Gatherer Lifestyle Tied to Low Atherosclerosis Risk
TUESDAY, May 22 (HealthDay News) -- Traditional hunter-gatherers have a lower risk of atherosclerosis, lower age-related increases in blood pressure, and reduced prevalence of hypertension, according to two studies published online May 21 in Hypertension.
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For Older Women, Saturated Fats Linked to Worse Cognition
TUESDAY, May 22 (HealthDay News) -- For older women, higher saturated fatty acid (SFA) intake correlates with worse global cognition and verbal memory trajectories, while higher intake of monounsaturated fatty acids (MUFA) correlates with improved trajectories, according to a study published online May 17 in the Annals of Neurology.
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CPAP Use May Reduce Risk of Hypertension in Apnea Patients
TUESDAY, May 22 (HealthDay News) -- For patients with obstructive sleep apnea (OSA) without daytime sleepiness, continuous positive airway pressure (CPAP) does not significantly affect the incidence of hypertension or cardiovascular events; however, regular use of CPAP may reduce the increased risk of incident hypertension seen among patients with OSA, according to two studies published in the May 23/30 issue of the Journal of the American Medical Association.
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Hair Loss Pathology Identified in Pityriasis Versicolor Lesions
TUESDAY, May 22 (HealthDay News) -- Patients with pityriasis versicolor (PV) lesions may experience hair thinning and/or loss within the lesion, according to a study published online May 10 in the Journal of the American Academy of Dermatology.
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Post-Stroke Inpatient Statins Improve Discharge Outcomes
TUESDAY, May 22 (HealthDay News) -- Statin use during hospitalization for ischemic stroke significantly improves the likelihood of being discharged to home or institution, according to a study published in the May 22 issue of Neurology.
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QRS Duration Independently Tied to Risk of Sudden Cardiac Death
TUESDAY, May 22 (HealthDay News) -- Prolonged QRS duration is associated with an increased risk of sudden cardiac death (SCD), according to a study published online May 21 in Circulation.
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Chemoradiotherapy Improves Survival for Elderly With NSCLC
TUESDAY, May 22 (HealthDay News) -- For elderly patients with locally advanced non-small-cell lung cancer (NSCLC), treatment with radiotherapy plus carboplatin improves overall survival versus radiotherapy alone, according to a study published May 22 in The Lancet Oncology.
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Vigorous Physical Activity Tied to Reduced Psoriasis Risk
TUESDAY, May 22 (HealthDay News) -- Vigorous physical activity is associated with a reduced risk of psoriasis in women, according to a study published online May 21 in the Archives of Dermatology.
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Weight Loss Reduces Potential Breast Cancer Biomarkers
TUESDAY, May 22 (HealthDay News) -- Postmenopausal weight loss through diet and the combination of diet and exercise is associated with a significant reduction in serum estrogens and free testosterone, according to a study published online May 21 in the Journal of Clinical Oncology.
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U.S. Task Force Recommends Against PSA-Based Screening
MONDAY, May 21 (HealthDay News) -- The U.S. Preventive Services Task Force (USPSTF) recommends against the use of the prostate-specific antigen (PSA)-based screening for men in the general U.S. population, according to new guidelines published online May 21 in the Annals of Internal Medicine.
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Dabrafenib Safe, Active Against Some Metastatic Melanomas
MONDAY, May 21 (HealthDay News) -- Dabrafenib, the mutant BRAF-selective inhibitor of BRAF kinase, is safe for treating solid tumors and shows antitumor activity against Val600-mutant BRAF melanomas and other solid tumors, including melanomas that have metastasized to the brain, according to a study published in the May 19 issue of The Lancet.
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Higher Pain Tolerance for Athletes Than Active Controls
MONDAY, May 21 (HealthDay News) -- Athletes seem to have significantly higher pain tolerance than normally-active people, according to research published in the June issue of Pain.
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Phylogenomic Analysis Reveals Origin, Spread of MRSA Clone
MONDAY, May 21 (HealthDay News) -- Phylogenomic analysis has revealed details about the emergence and transmission of a major methicillin-resistant Staphylococcus aureus (MRSA) clone, EMRSA-16, according to research published online May 14 in the Proceedings of the National Academy of Sciences.
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Folic Acid Enrichment May Reduce Specific Pediatric Cancers
MONDAY, May 21 (HealthDay News) -- Following mandatory folic acid fortification of enriched grain products in the United States in 1996 to 1998, there has been a decrease in the incidence of some childhood cancers, including Wilms tumor (WT) and primitive neuroectodermal tumors (PNETs), according to a study published online May 21 in Pediatrics.
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'Risky Music Behaviors' Linked to Other Risk Behaviors in Youth
MONDAY, May 21 (HealthDay News) -- Listening to loud music is highly associated with traditional health-risk behaviors in youth, including binge drinking and unprotected sex in frequent visitors to live music venues and cannabis use in MP3-player listeners, according to a study published online May 21 in Pediatrics.
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Parents of Children With Epilepsy Have Suboptimal Sleep
MONDAY, May 21 (HealthDay News) -- Parents of children with epilepsy often share a room or cosleep with their child, with both parents and child having suboptimal sleep and greater fatigue, according to a study published online May 17 in Epilepsia.
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Cardiac Disease Risk Factors Prevalent Among U.S. Teens
MONDAY, May 21 (HealthDay News) -- From 1999 to 2008 the prevalence of several cardiovascular disease risk factors remained stable among U.S. adolescents, but the burden of risk factors is still considerable, according to a study published online May 21 in Pediatrics.
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White Matter of Abstinent Alcoholics Recovers Over Time
MONDAY, May 21 (HealthDay News) -- Based on diffusion tensor imaging (DTI), the microstructural changes seen in the genu and body of the corpus callosum in recently detoxified alcohol-dependent patients are found to improve after one year of abstinence, according to research published online May 2 in Alcoholism: Clinical & Experimental Research.
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Instrumented Spinal Fusion Method Impacts Infection Rate
MONDAY, May 21 (HealthDay News) -- For patients who undergo instrumented spinal fusion, the rates of infection are higher among those who receive posterior lumbar interbody fusion compared with those who receive posterior or posterolateral fusion, according to a study published online May 10 in the Journal of Spinal Disorders & Techniques.
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Altered Amino Acid Metabolism Precedes Hyperglycemia
MONDAY, May 21 (HealthDay News) -- In a population of middle-aged men and women, branched-chain and aromatic amino acid metabolism alterations precede the development of hyperglycemia, and alanine, lactate, tyrosine, and pyruvate predict postchallenge glucose, according to a study published online May 4 in Diabetes Care.
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Palpitations Predict Future Atrial Fibrillation
FRIDAY, May 18 (HealthDay News) -- Palpitations, hypertension, and body mass index (BMI) are predictive of future atrial fibrillation (AF) in both men and women, according to a study published online May 15 in the European Journal of Preventive Cardiology.
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Workplace Inspections Reduce Job Injuries and Related Costs
FRIDAY, May 18 (HealthDay News) -- Government mandated workplace inspections, such as those carried out by California's Division of Occupational Safety and Health (Cal/OSHA) reduce on-the-job injuries and their associated costs without harming the companies' performance or profits, according to a study published in the May 18 issue of Science.
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Inadequate Pain Meds in ER for Patients With Long-Bone Fx
FRIDAY, May 18 (HealthDay News) -- The majority of patients with long-bone fractures receive inadequate pain medication in the emergency department, and disparities in management exist, according to a study published in the May issue of the Journal of Emergency Nursing.
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Epidemiology of Rosacea Described in United Kingdom
FRIDAY, May 18 (HealthDay News) -- The incidence of rosacea in the United Kingdom is 1.65 per 1,000 person-years, with alcohol consumption linked to a modest increase in risk and current smoking linked to an decreased risk, according to a study published online May 5 in the British Journal of Dermatology.
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Increase in Physical Activity in Men Optimizes Peak Bone Mass
FRIDAY, May 18 (HealthDay News) -- For young men, increasing physical activity over a five-year period is associated with improvements in bone mineral content (BMC) and bone mineral density (BMD), according to a study published in the May issue of the Journal of Bone and Mineral Research.
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'Pedicure Fish' May Harbor Pathogens for Zoonotic Disease
FRIDAY, May 18 (HealthDay News) -- Garra rufa (G. rufa), or doctor fish -- widely used in the health and beauty industries around the world, although currently banned in many U.S. states -- may harbor zoonotic disease pathogens, according to a letter to the editor published online May 16 in the U.S. Centers for Disease Control and Prevention's Emerging Infectious Diseases.
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Short-Term Smoke Exposure Impairs Endothelial Function
FRIDAY, May 18 (HealthDay News) -- Short-term exposure to low levels of secondhand smoke (SHS) results in a concentration-dependent decrease in endothelial function, according to a study published in the May 22 issue of the Journal of the American College of Cardiology.
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Recurrent HTN Seen for Half of Women With HTN in Pregnancy
FRIDAY, May 18 (HealthDay News) -- About half of women who experience a hypertensive disorder of pregnancy and late-preterm delivery develop a hypertensive disorder in a subsequent pregnancy, although few have delivery before 37 weeks in the subsequent pregnancy, according to a study published in the June issue of BJOG: An International Journal of Obstetrics & Gynaecology.
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Adjuvant Radiochemotherapy Has Lasting Benefit in Gastric Cancer
FRIDAY, May 18 (HealthDay News) -- Ten-year data from the Southwestern Oncology Group-directed Intergroup Study 0116 confirm the benefits of adjuvant radiochemotherapy after gastric cancer resection in terms of overall survival (OS) and relapse-free survival (RFS), according to research published online May 14 in the Journal of Clinical Oncology.
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Gender, High DAS28-P Index Predictive of Pain in Early RA
FRIDAY, May 18 (HealthDay News) -- For patients with rheumatoid arthritis (RA), female gender and having a high proportion of disease activity score (DAS28) attributable to patient-reported components (joint tenderness and visual analog score) (DAS28-P) at baseline are predictive of less improvement in pain at one year, according to a study published online May 3 in Arthritis Care & Research.
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Sunscreen Ingredient May Be Linked to Risk of Endometriosis
FRIDAY, May 18 (HealthDay News) -- Benzophenone (BP)-type derivatives may be linked to an increased risk of endometriosis, according to a study published in the April 17 issue of Environmental Science & Technology.
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Diet Intervention Most Useful in Reducing Pregnancy Weight Gain
FRIDAY, May 18 (HealthDay News) -- For pregnant women, dietary and lifestyle interventions are associated with a reduction in maternal gestational weight gain, with the largest reduction and improved pregnancy outcomes seen with dietary interventions, according to a review published online May 17 in BMJ.
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Generic Versions of Plavix Approved
THURSDAY, May 17 (HealthDay News) -- The first generic versions of Plavix (clopidogrel bisulfate) have been approved by the U.S. Food and Drug Administration.
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PEG Tubes Linked to Increased Risk of New Pressure Ulcers
THURSDAY, May 17 (HealthDay News) -- Percutaneous endoscopic gastrostomy (PEG) feeding tubes significantly increase the risk of new pressure ulcers and do not promote the healing of existing pressure ulcers in nursing home residents with advanced cognitive impairment, according to a study published in the May 14 issue of the Archives of Internal Medicine.
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Gene Expression Profile Testing Increasing in Breast Cancer
THURSDAY, May 17 (HealthDay News) -- From 2006 to 2008, the use of gene expression profile (GEP) testing increased, correlating with a decrease in the percentage of women with hormone receptor (HR)-positive breast cancer receiving adjuvant chemotherapy, according to a study published online May 14 in the Journal of Clinical Oncology.
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Retinal Vessel Diameter Linked to Heart Disease, Hypertension
THURSDAY, May 17 (HealthDay News) -- Baseline retinal vessel diameter is an independent predictor of incident hypertension, lower extremity arterial disease (LEAD), and any cardiovascular disease (CVD) at six years in African-American patients with type 1 diabetes mellitus, according to a study published in the May issue of the Archives of Ophthalmology.
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Causality Link Between HDL Cholesterol, MI Challenged
THURSDAY, May 17 (HealthDay News) -- Genetic mechanisms that are associated with high plasma levels of high-density lipoprotein (HDL) cholesterol do not reduce the risk of myocardial infarction (MI), adding question to causality of link, according to a study published online May 17 in The Lancet.
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Neurally Controlled Arm Lets Tetraplegics Reach, Grasp
THURSDAY, May 17 (HealthDay News) -- For tetraplegic individuals, use of a neural interface system is a feasible approach to direct robotic arm actions to reach and grasp, according to a letter published online May 16 in Nature.
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Statins Benefit Those at Low Risk for Vascular Events
THURSDAY, May 17 (HealthDay News) -- Reduction of low-density lipoprotein (LDL) cholesterol with statins is associated with a decrease in major vascular events, even for individuals with a five-year risk of less than 10 percent, according to research published online May 17 in The Lancet.
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Predictors of Length of Hospital Stay After Spine Surgery ID'd
THURSDAY, May 17 (HealthDay News) -- A variety of pre-, intra-, and postoperative factors contribute to increased length of stay (LOS) for patients who undergo level 1 minimally invasive (MIS) transforaminal interbody fusions (TLIF) spine surgery, according to a study published online May 8 in Spine.
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STAT3 Mutations ID'd in Rare Lymphoproliferative Disorder
THURSDAY, May 17 (HealthDay News) -- Approximately 40 percent of patients with T-cell large granular lymphocytic leukemia have mutations in the Src homology 2 (SH2) dimerization and activation domain of the signal transducer and activator of the transcription 3 (STAT3) gene, according to a study published in the May 17 issue of the New England Journal of Medicine.
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SNCA Variants Linked to Motor Function Decline in Parkinson's
WEDNESDAY, May 16 (HealthDay News) -- Variants of the alpha-synuclein gene (SNCA) are associated with a higher risk of a more rapid decline in motor function in patients with Parkinson's disease, according to a study published online May 15 in PLoS One.
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Coffee Drinking Linked to Lower Mortality Risk
WEDNESDAY, May 16 (HealthDay News) -- Coffee drinking is associated with a lower risk of death from most major causes except cancer, according to a study published in the May 17 issue of the New England Journal of Medicine.
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Leukoencephalopathy Risk Factors ID'd for MS Drug
WEDNESDAY, May 16 (HealthDay News) -- Multiple sclerosis patients taking natalizumab are at higher risk of developing progressive multifocal leukoencephalopathy (PML) if they are positive for the anti-JC virus antibodies, have been treated with immunosuppressants, and have been treated with natalizumab for longer periods, according to a study published in the May 17 issue of the New England Journal of Medicine.
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Azithromycin Tied to Increased Risk of Cardiovascular Mortality
WEDNESDAY, May 16 (HealthDay News) -- Azithromycin treatment is associated with an increased risk of cardiovascular and all-cause mortality, according to a study published in the May 16 issue of the New England Journal of Medicine.
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CDC: 35th Report on the Health of the Nation Published
WEDNESDAY, May 16 (HealthDay News) -- The 35th report on the health status of the United States in 2011 has been published online May 16 by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).
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Increased Sudden Cardiac Death Rate Among HIV Patients
WEDNESDAY, May 16 (HealthDay News) -- Patients with HIV/AIDS have a significantly increased risk of sudden cardiac death (SCD), according to a study published in the May 22 issue of the Journal of the American College of Cardiology.
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Repeated Revascularization Doesn't Aid High-Risk Patients
WEDNESDAY, May 16 (HealthDay News) -- For asymptomatic patients who are identified as high-risk by exercise echocardiography (ExE) after coronary revascularization, repeated revascularization is not associated with improved outcomes, according to a study published online May 14 in the Archives of Internal Medicine.
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Sex Influences Survival in Esophageal Cancer
WEDNESDAY, May 16 (HealthDay News) -- Sex is an independent prognostic factor for patients with locoregional esophageal cancer (LEC) and metastatic esophageal cancer (MEC), according to a study published online May 14 in the Journal of Clinical Oncology.
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Pazopanib Active in Metastatic Soft-Tissue Sarcoma
WEDNESDAY, May 16 (HealthDay News) -- For patients with metastatic non-adipocytic soft-tissue sarcoma, progressing in spite of previous chemotherapy, pazopanib improves progression-free survival, according to the results of a phase 3 study published online May 16 in The Lancet.
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Outcomes Good for Status Asthmaticus Patients in ICU
WEDNESDAY, May 16 (HealthDay News) -- Although the majority of patients admitted to the intensive care unit (ICU) with status asthmaticus (SA) require mechanical ventilation, the rates of mortality and complications are very low, according to a study published in the March issue of Respiratory Medicine.
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Diagonal Ear Lobe Crease Tied to Coronary Artery Disease
WEDNESDAY, May 16 (HealthDay News) -- Diagonal ear lobe crease (DELC) is independently and significantly associated with the prevalence, extent, and severity of coronary artery disease (CAD), according to a study published in the May 1 issue of The American Journal of Cardiology.
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Many People With Dementia Die at Home
WEDNESDAY, May 16 (HealthDay News) -- Individuals with dementia often live and die at home, and most transitions to a nursing home follow hospitalization, according to a study published in the May issue of the Journal of the American Geriatrics Society.
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More Education Linked to Lower Mortality in Over 40s
TUESDAY, May 15 (HealthDay News) -- Additional schooling is associated with a small reduction in mortality, but only after 40 years of age, according to a study published online May 14 in the Proceedings of the National Academy of Sciences.
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Air Pollution Linked to Cardiovascular Disease Markers
TUESDAY, May 15 (HealthDay News) -- Changes in air pollution levels during the Beijing Olympics were associated with changes in biomarkers linked to cardiovascular disease in healthy young people, according to a study published in the May 16 issue of the Journal of the American Medical Association, a theme issue on global health.
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AIDS Relief Assistance Linked to Greater Decline in Mortality
TUESDAY, May 15 (HealthDay News) -- All-cause adult mortality declined more substantially in African countries in which the U.S. President's Emergency Plan for AIDS Relief (PEPFAR) program operated more intensively between 2004 and 2008, according to a study published in the May 16 issue of the Journal of the American Medical Association, a theme issue on global health.
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Early Addition of Prenatal Micronutrients Ups Child Survival
TUESDAY, May 15 (HealthDay News) -- Poor, pregnant women who receive multiple micronutrient supplementation (MMS), including iron and folic acid, with early food supplementation, have substantially improved infant survival, compared to women in a standard program, according to a study published in the May 16 issue of the Journal of the American Medical Association, a theme issue on global health.
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Acupuncture Tied to Improved Dyspnea on Exertion in COPD
TUESDAY, May 15 (HealthDay News) -- For patients with chronic obstructive pulmonary disease (COPD), acupuncture appears to improve dyspnea on exertion, according to a study published online May 14 in the Archives of Internal Medicine.
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Low Back Pain Improves Soon After Treatment, but Still Lingers
TUESDAY, May 15 (HealthDay News) -- For patients with acute or persistent low back pain, pain and disability improve in the first six weeks of treatment, but low-to-moderate pain and disability tend to persist at one year, according to a review published online May 14 in CMAJ, the journal of the Canadian Medical Association.
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Better Outcomes at High-Volume Stroke Centers
TUESDAY, May 15 (HealthDay News) -- High-volume endovascular stroke centers provide faster times to treatment, and patients are more likely to have good clinical outcomes and successful reperfusion, according to a study published online May 13 in the Journal of NeuroInterventional Surgery.
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Peptide Level Ups Diagnosis of Heart Failure in Primary Care
TUESDAY, May 15 (HealthDay News) -- For patients presenting with dyspnea, the additional measurement of B-type natriuretic peptide (BNP) levels increases the certainty of diagnosis of heart failure and accelerates initiation of appropriate treatment, but does not reduce medical costs, according to a study published online May 2 in the Journal of Internal Medicine.
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Lack of Post-MI Discharge Advice Hinders Sexual Activity
TUESDAY, May 15 (HealthDay News) -- Less than half of patients who suffer an acute myocardial infarction (AMI) receive instruction regarding resuming sexual activity on hospital discharge, with those who do not receive instruction more likely to report loss of sexual activity, according to a study published in the May 15 issue of The American Journal of Cardiology.
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U.S. Lifetime Prevalence of Sleep Walking ~30 Percent
TUESDAY, May 15 (HealthDay News) -- The lifetime prevalence of nocturnal wandering with abnormal state of consciousness (NW) is approximately 30 percent in the U.S. general population, according to a study published in the May 15 issue of Neurology.
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Trail Making Test Performance Predicts Post-Stroke Mortality
TUESDAY, May 15 (HealthDay News) -- Poor executive performance, as measured with the Trail Making Test (TMT)-A and -B, can identify elderly men who are at higher risk of death after a first-ever stroke, according to a study published online May 9 in BMJ Open.
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Small Benefit of Inhaled Corticosteroids for Sinusitis
TUESDAY, May 15 (HealthDay News) -- For patients with acute sinusitis, inhaled corticosteroids provide a small benefit over placebo but only after several weeks, according to a study published in the May/June issue of the Annals of Family Medicine.
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Screening for Retinopathy Every Two Years Deemed Safe
TUESDAY, May 15 (HealthDay News) -- For patients with type 2 diabetes without evidence of retinopathy, increasing the screening interval to every two years yields no increased risk of retinopathy-mediated vision loss and reduces screening costs, according to a study published online May 7 in Diabetes Care.
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PET More Sensitive Than CT for Merkel Cell Carcinoma
TUESDAY, May 15 (HealthDay News) -- Fluorine-18-fluorodeoxyglucose (F-18-FDG) positron emission tomography (PET) is significantly more sensitive and equally specific compared with traditional computed tomography (CT) imaging for evaluation of the regional lymph node basin in patients with Merkel cell carcinoma (MCC), according to research published online May 2 in the Journal of the American Academy of Dermatology.
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Being Fit Lowers HTN Risk in Those With Parental History
MONDAY, May 14 (HealthDay News) -- Having a moderate or high level of fitness can attenuate the increased risk of developing hypertension due to parental history, according to a study published online May 14 in Hypertension.
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Smoking Cannabis Reduces Spasticity in Multiple Sclerosis
MONDAY, May 14 (HealthDay News) -- Smoking cannabis is associated with a reduction in spasticity for patients with multiple sclerosis (MS), according to a study published online May 14 in CMAJ, the journal of the Canadian Medical Association.
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Sumatriptan/Naproxen Helpful in Treating Teens' Migraines
MONDAY, May 14 (HealthDay News) -- Treatment with sumatriptan and naproxen sodium (suma/nap) is well tolerated and effective in reducing migraine pain in adolescents, according to a study published online May 14 in Pediatrics.
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CT Colonography Accurate for 10 mm Adenomas
MONDAY, May 14 (HealthDay News) -- For patients at average-to-moderate risk of colon cancer, computed tomographic colonography (CTC) accurately detects adenomas 10 mm or larger, but not smaller lesions, according to a study published in the May 15 issue of the Annals of Internal Medicine.
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Batteries Increasing Culprit of ER Visits Among Young Boys
MONDAY, May 14 (HealthDay News) -- The number of emergency department visits for battery-related incidents is rising significantly, particularly in boys under the age of 5 years, according to a study published online May 14 in Pediatrics.
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Youth With ASD Have Poor Postsecondary Outcomes
MONDAY, May 14 (HealthDay News) -- Youth with autism spectrum disorders (ASDs) are at high risk for not participating in postsecondary education or employment, particularly in the first two years after high school, according to a study published online May 14 in Pediatrics.
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Walking While Bottle Drinking Causes Injuries in Toddlers
MONDAY, May 14 (HealthDay News) -- Approximately 2,000 injuries occur each year from toddlers falling with a bottle, pacifier, or sippy cup in their mouth, according to a study published online May 14 in Pediatrics.
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Psychiatric Patients Wait Average of 11.5 Hours in ER
MONDAY, May 14 (HealthDay News) -- Average emergency department wait times for adult patients with psychiatric emergencies is 11.5 hours, and can be even longer for those who are older, uninsured, or intoxicated, according to research published online May 4 in the Annals of Emergency Medicine.
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Thrombus Aspiration in Primary PCI Has No Effect on Outcomes
MONDAY, May 14 (HealthDay News) -- The use of manual or mechanical thrombus aspiration (TA) in adjunct to primary percutaneous coronary intervention (PPCI) does not affect the two-year incidence of major adverse cardiac events in patients with acute ST-segment elevation myocardial infarction (STEMI), according to a study published in the May 1 issue of Catheterization & Cardiovascular Interventions.
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New Technique Removes Inoperable Abdominal Tumors
FRIDAY, May 11 (HealthDay News) -- Multivisceral ex vivo surgery can successfully remove invasive abdominal tumors previously deemed unresectable due to location and vascular involvement, according to a case report published in the May issue of the American Journal of Transplantation.
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Post-SES Implantation, Statins Prevent Late Revascularization
FRIDAY, May 11 (HealthDay News) -- For patients who undergo sirolimus-eluting stent (SES) implantation, use of statin therapy is associated with a reduced risk of late target lesion revascularization (TLR), according to a study published in the May 15 issue of The American Journal of Cardiology.
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Genetic Profile of Circulating Tumor Cells Is Heterogeneous
FRIDAY, May 11 (HealthDay News) -- Gene expression of circulating tumor cells (CTCs), rare cells in the blood of patients with solid tumors, is heterogeneous and is distinct from the profiles of single cells from cancer cell lines commonly used to study cancer, according to a study published online May 7 in PLoS One.
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Global Deaths in Children Under 5 Down Since 2000
FRIDAY, May 11 (HealthDay News) -- From 2000 to 2010, there was a decrease in the global burden of death in children younger than 5 years of age, according to a study published online May 11 in The Lancet.
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African-Americans Have More Severe Sclerosis Complications
FRIDAY, May 11 (HealthDay News) -- African-American patients with systemic sclerosis have more severe complications than Caucasian patients, and these complications are related to the type of autoantibody and severity of lung disease, according to a study published online May 10 in Arthritis & Rheumatism.
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Blood Clot Risk Elevated in Patch and Vaginal Ring Users
FRIDAY, May 11 (HealthDay News) -- Compared to nonusers of hormonal contraception, women who use combined contraceptive transdermal patches are at an eight-fold increased risk of venous thrombosis, and vaginal ring users are at a more than six-fold increased risk, according to a study published online May 10 in BMJ.
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Elective Induction of Labor Tied to Reduced Perinatal Mortality
FRIDAY, May 11 (HealthDay News) -- Elective induction of labor between 37 and 41 weeks of gestation is associated with a reduction in perinatal mortality but an increase in admission to neonatal units, compared with expectant management, according to a study published online May 10 in BMJ.
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Brain Stimulation Improves Brain Function in Alzheimer's
FRIDAY, May 11 (HealthDay News) -- Deep brain stimulation can improve brain connectivity and function in patients with mild Alzheimer's disease, and having a greater purpose in life reduces the effect of Alzheimer's pathology on cognitive function, according to one study published online May 7 in the Archives of Neurology and another study published in the May issue of the Archives of General Psychiatry.
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Rituximab Little Use in Resistant Idiopathic Nephrotic Syndrome
FRIDAY, May 11 (HealthDay News) -- The anti-CD20 monoclonal antibody, rituximab, added to prednisone and calcineurin inhibitors, does not provide any additional benefit in terms of reduced proteinuria in the treatment of children with resistant idiopathic nephrotic syndrome (INS), according a study published online May 10 in the Journal of the American Society of Nephrology.
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DNA Methylation Level Is Marker of Breast Cancer Risk
FRIDAY, May 11 (HealthDay News) -- Women with high levels of white blood cell (WBC) DNA methylation at the ATM loci have a significantly increased risk of breast cancer, regardless of family history or menopausal status, according a study published in the May 1 issue of Cancer Research.
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Sun Protective Behavior on the Rise in U.S. Adults
THURSDAY, May 10 (HealthDay News) -- Adults in the United States may be taking more precautions to avoid sunburn outdoors, but many are still getting burned, and a substantial proportion are utilizing indoor tanning, according to research published in the May 11 issue of the U.S. Centers for Disease Control and Prevention's Morbidity & Mortality Weekly Report.
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Mid- and Late-Life Depression Tied to Dementia Risk
THURSDAY, May 10 (HealthDay News) -- Patients with depressive symptoms either in midlife or late in life are at increased risk of developing dementia, according to a study published in the May issue of the Archives of General Psychiatry.
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Team-Centered Multicondition Care Deemed Cost-Effective
THURSDAY, May 10 (HealthDay News) -- For adults with depression and poorly controlled diabetes and/or coronary heart disease (CHD), a collaborative care intervention is cost-effective, according to a study published in the May issue of the Archives of General Psychiatry.
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Nonmedical Prescription Pain Medication Use Peaks at Age 16
THURSDAY, May 10 (HealthDay News) -- Use of prescription pain relievers to get high or for other nonmedical purposes (extramedical use) peaks around age 16 years, according to a study published online May 7 in the Archives of Pediatrics & Adolescent Medicine.
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Substantial Survival for Older Adults With Diabetes
THURSDAY, May 10 (HealthDay News) -- Middle-aged and older adults with diabetes have substantial five-year survival, with survival exceeding 50 percent for almost all age and clinical groups, according to a study published online April 6 in The Journals of Gerontology: Series A.
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Less Testing in ER for Children With Non-Private Insurance
THURSDAY, May 10 (HealthDay News) -- For children in the emergency department, non-private insurance status is associated with decreased diagnostic testing and interventions, according to a study published online May 10 in The Journal of Pediatrics.
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Lowest Fused Vertebral Level Linked to Motion in Scoliosis
THURSDAY, May 10 (HealthDay News) -- For postoperative patients with adolescent idiopathic scoliosis (AIS), preservation of vertebral motion segments allows for greater distribution of functional motion, according to a study published in the May 1 issue of Spine.
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Glycemic Variability Affects Mood and Quality of Life
THURSDAY, May 10 (HealthDay News) -- Glycemic variability appears to be associated with lower quality of life and negative moods in women with type 2 diabetes, according to a study published in the March 30 issue of Diabetes Technology & Therapeutics.
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JAM-A Has Inhibitory Role in Platelets
THURSDAY, May 10 (HealthDay News) -- A platelet protein, junctional adhesion molecule A (JAM-A), inhibits integrin outside-in signaling and prevents premature platelet activation, according to a study published in the April 5 issue of Blood.
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Avastin and Lucentis Equally Improve Visual Acuity in AMD
WEDNESDAY, May 9 (HealthDay News) -- Avastin (bevacizumab) and Lucentis (ranibizumab) have similar effects on visual acuity in age-related macular degeneration (AMD), according to a study published online May 2 in Ophthalmology.
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Review: Physical Activity Cuts Mortality for Cancer Survivors
WEDNESDAY, May 9 (HealthDay News) -- Physical activity correlates with reduced all-cause and breast and colon cancer-specific mortality, according to a study published online May 8 in the Journal of the National Cancer Institute.
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Epilepsy Treatment Response Patterns Usually Constant
WEDNESDAY, May 9 (HealthDay News) -- The response that newly-diagnosed epilepsy patients have to their first drug treatment may indicate their likelihood of achieving seizure freedom, according to a study published online May 9 in Neurology.
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New Technique Predicts Prostate Cancer Relapse
WEDNESDAY, May 9 (HealthDay News) -- Copy number variation (CNV) in both malignant and benign prostate tissue is predictive of prostate cancer relapse, according to a study published online May 9 in The American Journal of Pathology.
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Infectious Agents Cause About One in Six Cancers Worldwide
WEDNESDAY, May 9 (HealthDay News) -- Globally, nearly two million new cancer cases are caused by infectious agents each year, according to a study published online May 9 in The Lancet Oncology.
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IUDs Highly Effective As Emergency Contraception
WEDNESDAY, May 9 (HealthDay News) -- Intrauterine devices (IUDs) are a highly effective form of emergency contraception, according to research published online May 8 in Human Reproduction.
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Metformin May Have Dual Effect in Breast Cancer
WEDNESDAY, May 9 (HealthDay News) -- For women without diabetes and with operable breast cancer, administration of metformin prior to surgery does not significantly affect the proliferative marker Ki-67 overall, but drug effects are observed according to homeostasis model assessment (HOMA), particularly in luminal B tumors, according to a study published online May 7 in the Journal of Clinical Oncology.
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Health-Related QoL Evaluated for Children With Brain Tumors
WEDNESDAY, May 9 (HealthDay News) -- In children and adolescents with brain tumors treated with proton radiation, health-related quality of life (HRQoL) scores are affected by both disease type and treatment, with assessments made by the patients correlating well with those of their parents, according to a study published online May 7 in the Journal of Clinical Oncology.
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Pediatric Content in Drug Labeling Has Increased
WEDNESDAY, May 9 (HealthDay News) -- Pediatric content in the labeling of drugs has improved from 1975 to 1999, but still only 46 percent of drug labeling in the electronic Physicians' Desk Reference (ePDR) includes pediatric information, according to research published in the May 9 issue of the Journal of the American Medical Association.
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Amino Acid Levels Linked to Type 2 Diabetes Risk
WEDNESDAY, May 9 (HealthDay News) -- Levels of some amino acids are associated with glycemia and insulin resistance and predict the development of type 2 diabetes in men, according to a study published online May 2 in Diabetes.
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High Infection Rates Seen in Juvenile Idiopathic Arthritis
WEDNESDAY, May 9 (HealthDay News) -- Children with juvenile idiopathic arthritis (JIA) have higher rates of hospitalized bacterial infection than children without the condition, and high-dose steroids significantly increase the rate of infection, according to a study published online May 8 in Arthritis & Rheumatism.
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Long Auto Commutes Found to Be Hazardous to Health
WEDNESDAY, May 9 (HealthDay News) -- Commuting distance is negatively associated with physical activity and cardiorespiratory fitness (CRF), and positively associated with obesity and metabolic risk indicators, according to a study published online May 8 in the American Journal of Preventive Medicine.
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Chromosomal Screening Improves IVF Pregnancy Rates
WEDNESDAY, May 9 (HealthDay News) -- Screening embryos produced by in vitro fertilization using array comparative genomic hybridization (aCGH) plus morphology improves pregnancy rates over screening by morphology alone in single embryo transfers, according to a study published online May 2 in Molecular Cytogenetics.
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Lack of Sleep Not Necessarily Detrimental to Surgical Skills
WEDNESDAY, May 9 (HealthDay News) -- Sleep-deprived medical students are able to perform and learn surgical skills, although they have an increased total subjective mental workload, according to a study published in the January issue of the American Journal of Surgery.
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Probiotics Helpful in Reducing Antibiotic-Related Diarrhea
TUESDAY, May 8 (HealthDay News) -- Probiotics seem to be effective in preventing and treating antibiotic-associated diarrhea (AAD), but more research is needed to know which probiotics are most effective for specific antibiotics, according to research published in the May 9 issue of the Journal of the American Medical Association.
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Poor Health Status Indicators ID'd for Patients With ICDs
TUESDAY, May 8 (HealthDay News) -- Implantable cardioverter defibrillator (ICD) shock status and Type D personality are indicators of post-implantation health status at one-year follow-up, according to a study published online May 8 in Circulation: Cardiovascular Quality and Outcomes.
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Older Women With A-Fib at Greater Stroke Risk Than Men
TUESDAY, May 8 (HealthDay News) -- The risk of stroke following a recent diagnosis of atrial fibrillation (AF) in older patients is higher in women than men, regardless of warfarin use, according to a study published in the May 9 issue of the Journal of the American Medical Association.
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Newer Model Better Identifies eGFR-Related Risks
TUESDAY, May 8 (HealthDay News) -- The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation more accurately identifies the risk implications of estimated glomerular filtration rate (eGFR) than the Modification of Diet in Renal Disease (MDRD) Study equation, according to research published in the May 9 issue of the Journal of the American Medical Association.
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Living Close to Major Roadway at Time of MI Ups Mortality
TUESDAY, May 8 (HealthDay News) -- For survivors of acute myocardial infarction (AMI), residential proximity to a major roadway at the time of AMI is linked to an increased risk of 10-year mortality, according to a study published in the May 8 issue of Circulation.
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Sun/Skin Cancer Counseling Recommended for Youth
TUESDAY, May 8 (HealthDay News) -- The U.S. Preventive Services Task Force (USPSTF) recommends that physicians counsel children, adolescents, and young adults who have fair skin about ultraviolet radiation exposure and skin cancer prevention, according to new recommendations published online May 7 in the Annals of Internal Medicine.
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Self-Disclosure Linked to Activation of Reward in Brain
TUESDAY, May 8 (HealthDay News) -- Self-disclosure is associated with increased activation in regions of the brain linked with reward, according to research published online May 7 in the Proceedings of the National Academy of Sciences.
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Television Viewing Linked to Unhealthy Eating in U.S. Teens
TUESDAY, May 8 (HealthDay News) -- Among U.S. adolescents, television viewing is associated with unhealthy eating behaviors, according to a study published in the May issue of the Archives of Pediatrics & Adolescent Medicine.
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Inexact Perception, but Most Moms Happy With Toddler Size
TUESDAY, May 8 (HealthDay News) -- Although most mothers are inaccurate in their perception of their toddler's weight, they are mainly satisfied with their toddler's body size, according to a study published in the May issue of the Archives of Pediatrics & Adolescent Medicine.
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Tenofovir Disoproxil Fumarate Doesn't Impact Fetal Growth
TUESDAY, May 8 (HealthDay News) -- Maternal use of the anti-HIV drug tenofovir disoproxil fumarate (TDF) does not affect fetal growth but may lead to a delayed effect on infant growth in the first year, according to a study published online Feb. 29 in AIDS.
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Oxygen Treatment Beneficial in Diabetes-Prone Mice
TUESDAY, May 8 (HealthDay News) -- Hyperbaric oxygen treatment of a preclinical diabetes mouse model reduces the incidence of diabetes and preserves insulin-producing β-cells, according to a study published online May 7 in Diabetes.
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New Meningitis B Vaccine Strongly Immunogenic
MONDAY, May 7 (HealthDay News) -- A new meningococcus serogroup B vaccine is strongly immunogenic against multiple strains and well tolerated in healthy adolescents, according to a study published online May 7 in The Lancet Infectious Diseases.
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Screening for Intimate Partner Violence Proves Beneficial
MONDAY, May 7 (HealthDay News) -- Screening instruments can be used in the health care setting to accurately identify women who are experiencing intimate partner violence (IPV), with minimal adverse effects, according to a review published online May 7 in the Annals of Internal Medicine.
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Exercise Training Reduces Muscle Proteolysis in CHF
MONDAY, May 7 (HealthDay News) -- Increased expression of MuRF-1, a component of the ubiquitin-proteasome system, is associated with chronic heart failure, and exercise training reduces MuRF-1 levels, according to a study published online May 7 in Circulation.
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Zinc May Shorten Duration of Common Cold in Adults
MONDAY, May 7 (HealthDay News) -- Oral zinc may shorten the duration of symptoms associated with the common cold in adults, but adverse effects are common, according to a review published online May 7 in CMAJ, the journal of the Canadian Medical Association.
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Resistance Patterns of Urinary E. coli Isolates Changing
MONDAY, May 7 (HealthDay News) -- The antimicrobial resistance of urinary Escherichia coli (E. coli) isolates to ciprofloxacin and trimethoprim-sulfamethoxazole (TMP-SMX) increased substantially from 2000 to 2010, according to a study published in the April issue of Antimicrobial Agents and Chemotherapy.
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Hospitals Lack Hand Surgeons for Emergencies
MONDAY, May 7 (HealthDay News) -- There is a shortage of hand specialists to provide emergency coverage in the state of Tennessee, according to research published in the May issue of the Annals of Plastic Surgery.
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Computer-Based Screening May Reduce Teen Substance Abuse
MONDAY, May 7 (HealthDay News) -- A computer-facilitated screening and provider brief advice (cSBA) system for primary care can increase adolescent receipt of substance use screening across a variety of practice settings, according to a study published online May 7 in Pediatrics.
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Modified Fluorene Compound Potently Disrupts Amyloid-β
MONDAY, May 7 (HealthDay News) -- A modified version of fluorene counteracts amyloid beta (Aβ) peptide toxicity, and is more potent than the original fluorene compounds, according to a study published online April 30 in PLoS One.
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School Vaccination Requirements Up Coverage
MONDAY, May 7 (HealthDay News) -- Middle school entry vaccination requirements may increase coverage for adolescent vaccines, but education-only requirements do not appear to have an impact, according to a study published online May 7 in Pediatrics.
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Maternal Dietary Counseling Improves Child Nutrition
MONDAY, May 7 (HealthDay News) -- The delivery of home-based maternal counseling focusing on breastfeeding and complementary feeding to low-income mothers during their child's first year of life significantly improves the lipid profile in girls at 7 to 8 years of age, according to a study published online May 7 in Pediatrics.
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Pleasure Eating Stimulates Chemical Reward System
FRIDAY, May 4 (HealthDay News) -- Pleasure eating is associated with increased peripheral levels of two endogenous rewarding mediators, according to a pilot study published online March 22 in the Journal of Clinical Endocrinology & Metabolism.
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Computer Use + Exercise Lower Mild Cognitive Impairment Risk
FRIDAY, May 4 (HealthDay News) -- The combination of engaging in moderate exercise and using a computer significantly reduces the likelihood of mild cognitive impairment (MCI) among the elderly, according to a study published in the May issue of the Mayo Clinic Proceedings.
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T Cell-Based HIV Gene Therapy Safe Over Long Term
FRIDAY, May 4 (HealthDay News) -- T cell-based gene therapy for HIV seems safe, with no evidence of vector-induced cell immortalization more than a decade after treatment, according to a study published in the May 2 issue of Science Translational Medicine.
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Hospitals Procure More Alcohol Rub, Soap During Campaign
FRIDAY, May 4 (HealthDay News) -- The implementation of the Cleanyourhands campaign increased procurement of alcohol rub and soap, which is associated with decreased rates of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia and Clostridium difficile ( C. difficile) infection, according to a study published online May 3 in BMJ.
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Gene Variants Linked to Hot Flashes in Women Who Smoke
FRIDAY, May 3 (HealthDay News) -- Variants in genes that metabolize sex steroids are associated with a greater frequency or severity of hot flashes in older women who smoke, according to a study published online March 30 in the Journal of Clinical Endocrinology & Metabolism.
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FISH + Cytology Beats Cytology Alone for Neoplasia Detection
FRIDAY, May 4 (HealthDay News) -- For patients with diverse pathologies who undergo endoscopic ultrasonography with fine-needle aspiration, adding fluorescence in situ hybridization (FISH) detection methods to conventional cytology improves the sensitivity of cytology alone for detection of neoplastic lesions, according to a study published in the May issue of Gastroenterology.
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Lupus Nephritis Screening and Management Guidelines Issued
FRIDAY, May 4 (HealthDay News) -- The American College of Rheumatology has produced new guidelines for the screening, treatment, and management of lupus nephritis; the guidelines have been published in the June issue of Arthritis Care & Research.
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Training Helps OR Nurses Manage Disruptive Physician Behavior
FRIDAY, May 4 (HealthDay News) -- Communication skills training may help nurses manage disruptive physician behavior, according to a study published in the May issue of the AORN Journal.
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CMS Policy Helping Hospitals to Prevent Targeted Infections
FRIDAY, May 4 (HealthDay News) -- Hospitals seem to be paying greater attention to preventing targeted health care-associated infections (HAIs) as a result of the Centers for Medicare and Medicaid Services (CMS) nonpayment policy, according to a study published in the May issue of the American Journal of Infection Control.
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Complementary Medicine Not Tied to Prostate Cancer Outcome
FRIDAY, May 4 (HealthDay News) -- Although widely used, complementary and alternative medicine (CAM) does not impact patient satisfaction with treatment or patient-reported outcomes after treatment for localized prostate cancer, according to a study published in the May issue of Urology.
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Many COPD Comorbidities Independently Tied to Mortality
FRIDAY, May 4 (HealthDay News) -- Twelve comorbidities that include cancer and cardiovascular problems are associated with a higher risk of death in patients with chronic obstructive pulmonary disease (COPD), according to a study published online May 3 in the American Journal of Respiratory and Critical Care Medicine.
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New Guidelines for Aneurysmal Subarachnoid Bleeds Issued
THURSDAY, May 3 (HealthDay News) -- The latest evidence emphasizes early and aggressive care for emergency room patients diagnosed with aneurysmal subarachnoid hemorrhage (aSAH), according to revised treatment guidelines issued by the American Heart Association (AHA) and the American Stroke Association and published online May 3 in Stroke.
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CDC: Teen Birth Rate Decreasing in United States
THURSDAY, May 3 (HealthDay News) -- From 1990 to 2006-2010, the teen birth rate declined among U.S. females, according to a study published in the May 4 issue of the U.S. Centers for Disease Control and Prevention's Morbidity & Mortality Weekly Report.
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Antipsychotic Maintenance Rx Aids Schizophrenia Patients
THURSDAY, May 3 (HealthDay News) -- Maintenance therapy with antipsychotic drugs is associated with a reduction in the relapse rate in schizophrenia, but benefits must be weighed against risks of adverse side effects, according to a review published online May 3 in The Lancet.
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Problem Behavior Up Among Children Born Post-Term
THURSDAY, May 3 (HealthDay News) -- Children born post-term have an increased risk of problem behavior and are more likely to have clinical attention-deficit/hyperactivity disorder in early childhood, according to a study published online May 2 in the International Journal of Epidemiology.
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Office Evaluation Comparable to Pre-Op Urodynamic Testing
THURSDAY, May 3 (HealthDay News) -- For women with uncomplicated stress incontinence, preoperative office evaluation alone is noninferior to urodynamic testing with respect to success of treatment at one year, according to a study published online May 2 in the New England Journal of Medicine.
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TAVI Is a Reasonable Option for High-Risk Elderly Patients
THURSDAY, May 3 (HealthDay News) -- For high-risk elderly patients with aortic stenosis, transcatheter aortic-valve implantation (TAVI) is a reasonable option, according to a study published in the May 3 issue of the New England Journal of Medicine.
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Peers Influence Both Pro- and Anti-Alcohol Behavior
THURSDAY, May 3 (HealthDay News) -- Adolescents are very adaptable to changing their alcohol norms based on those of their peers, especially peers of high-status, who may successfully either encourage or discourage alcohol use, according to a study published online April 17 in Alcoholism: Clinical and Experimental Research.
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Low Vitamin D Linked to Poorer Outcomes in Lung Recipients
THURSDAY, May 3 (HealthDay News) -- For lung transplant recipients, 25-hydroxyvitamin D (25[OH]D) deficiency is associated with increased incidence of acute rejection and infection, and deficiency at one year after transplant is linked with increased mortality, according to a study published online March 5 in The Journal of Heart and Lung Transplantation.
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Odor Receptor Genotype May Be Cause of Meat Aversion
THURSDAY, May 3 (HealthDay News) -- Having two copies of a functional odor receptor gene variant (OR7D4 RT) is associated with increased sensitivity to androstenone, and androstenone-containing meat, according to a study published online May 2 in PLoS One.
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Recent Improvement in 3D ECHO Accuracy for LV Mass
THURSDAY, May 3 (HealthDay News) -- In the past decade there has been an improvement in the accuracy of three-dimensional echocardiography (3DE) for measurement of left ventricular (LV) mass, according to a meta-analysis published online April 30 in The American Journal of Cardiology.
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Perioperative Interruptions Lead to Miscommunication
THURSDAY, May 3 (HealthDay News) -- The number of miscommunications that occur during surgery is inversely associated with the length of time a team has worked together, and positively associated with the number of interruptions during surgery, according to a study published in the May issue of the AORN Journal.
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Generally No Link Between Prenatal Smoking and Autism
THURSDAY, May 3 (HealthDay News) -- Generally there is no association between maternal smoking during pregnancy and risk of the child developing autism spectrum disorders (ASDs), although there may be a link between smoking and development of high-functioning autism, according to a study published online April 25 in Environmental Health Perspectives.
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For Thyroid Cancer, Thyrotropin + Low-Dose Radioiodine Effective
THURSDAY, May 3 (HealthDay News) -- For patients with thyroid cancer who undergo complete surgical resection, low-dose radioiodine plus thyrotropin is as effective as high-dose radioiodine, according to two studies published in the May 3 issue of the New England Journal of Medicine.
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Endotoxemia Influenced by Diet Type
THURSDAY, May 3 (HealthDay News) -- A Western-style diet is associated with increased levels of endotoxin activity (endotoxemia), and a prudent-style diet (containing moderately greater amounts of omega-3 fatty acids, vitamin C, and vitamin E than the Western-style diet) is linked to reduced endotoxemia, according to a study published in the May issue of Gastroenterology.
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Omega-3 Intake Linked With Reduced Plasma β-Amyloid 42
WEDNESDAY, May 2 (HealthDay News) -- Higher intake of ω-3 polyunsaturated fatty acid (PUFA) is correlated with lower plasma levels of β-amyloid (Aβ)42, according to a study published online May 2 in Neurology.
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Early Noninvasive Paternity Test Based on SNPs Is Accurate
WEDNESDAY, May 2 (HealthDay News) -- A new test, based on single-nucleotide polymorphisms, that only requires a maternal blood sample can correctly identify paternity as early as 8 weeks' gestation, according to a letter published in the May 3 issue of the New England Journal of Medicine.
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Body Fat Linked to Reduced Fracture Risk for Women
WEDNESDAY, May 2 (HealthDay News) -- Higher body fat mass is associated with a reduced risk of fracture among women, but not men, according to a study published in the May issue of the Journal of Internal Medicine.
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No Adverse Effect of Weekend, Nighttime Liver Transplants
WEDNESDAY, May 2 (HealthDay News) -- Performing liver transplantation procedures at night or on weekends does not appear to affect patient or liver graft survival, according to research published in the May issue of Liver Transplantation.
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Lower All-Cause, Cardio Mortality in Obese With RA
WEDNESDAY, May 2 (HealthDay News) -- Overweight and obese patients with rheumatoid arthritis (RA) have lower all-cause and cardiovascular mortality, but have substantially increased risks of comorbidities, medical costs, and reduced quality of life compared with normal-weight RA patients, according to a study published online April 18 in Arthritis Care & Research.
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Erlotinib Plus Chemo Doesn't Improve Efficacy in NSCLC
WEDNESDAY, May 2 (HealthDay News) -- Adding chemotherapy with carboplatin plus paclitaxel to the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor erlotinib does not improve efficacy in the treatment of chemotherapy-naive, never or light former smokers with advanced non-small-cell lung cancer (NSCLC), according to a study published online April 30 in the Journal of Clinical Oncology.
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Pulse Oximetry IDs Critical Congenital Heart Defects
WEDNESDAY, May 2 (HealthDay News) -- Pulse oximetry has high specificity, moderate sensitivity, and low false-positive rates for detecting critical congenital heart defects in asymptomatic newborns, according to a systematic review and meta-analysis published online May 2 in The Lancet.
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Nonsupportive Family Members Sabotage Diabetes Self-Care
WEDNESDAY, May 2 (HealthDay News) -- Diabetes patients with nonsupportive family members are less adherent to their diabetes medication regimen and have worse glycemic control, according to a study published online April 26 in Diabetes Care.
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Chemo Combination Promising for Multiple Myeloma
WEDNESDAY, May 2 (HealthDay News) -- For patients with relapsed or refractory multiple myeloma, combination treatment with elotuzumab, lenalidomide, and low-dose dexamethasone is generally well tolerated, with encouraging response rates, according to a study published online April 30 in the Journal of Clinical Oncology.
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Asthma Has Adverse Effect on Physical Health in Elderly
WEDNESDAY, May 2 (HealthDay News) -- Older adults with asthma have decreased lung function, increased rates of allergic sensitization, and worse quality of life than healthy controls, according to a study published in the May issue of the Annals of Allergy, Asthma & Immunology.
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Causal Link ID'd Between BMI, Ischemic Heart Disease
WEDNESDAY, May 2 (HealthDay News) -- The positive association between body mass index (BMI) and ischemic heart disease (IHD) is likely to be causal, according to a study published online May 1 in PLoS Medicine.
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In CKD, Fish Oil Doesn't Up Hemodialysis Graft Patency
TUESDAY, May 1 (HealthDay News) -- For patients with stage 5 chronic kidney disease, fish oil does not improve synthetic hemodialysis graft patency, according to a study published in the May 2 issue of the Journal of the American Medical Association.
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Breast Brachytherapy May Not Be Best Choice in Older Women
TUESDAY, May 1 (HealthDay News) -- For older women with invasive breast cancer, treatment with brachytherapy following a lumpectomy is associated with a decreased likelihood of long-term breast preservation and an increased likelihood of complications, but no difference in overall survival, compared to whole-breast irradiation (WBI) treatment, according to a study published in the May 2 issue of the Journal of the American Medical Association.
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Methodological Heterogeneity Seen in Clinical Trials
TUESDAY, May 1 (HealthDay News) -- Clinical studies registered with ClinicalTrials.gov from 2007 and 2010 are predominately small, single-center trials and contain significant heterogeneity in methodology, according to a study published in the May 2 issue of the Journal of the American Medical Association.
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A Third of Adults With Arthritis Have Anxiety, Depression
TUESDAY, May 1 (HealthDay News) -- One-third of U.S. adults with physician-diagnosed arthritis report having anxiety or depression, with anxiety more prevalent than depression, according to a study published online May 1 in Arthritis Care & Research.
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Women Have Clear Melanoma Survival Advantage Over Men
TUESDAY, May 1 (HealthDay News) -- Women with localized melanoma have a consistent advantage over men of approximately 30 percent for survival and progression, according to a study published online April 30 in the Journal of Clinical Oncology.
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Indirect Link ID'd Between Pain Catastrophizing, Severity
TUESDAY, May 1 (HealthDay News) -- Pain catastrophizing, in particular ruminating about pain, has an indirect effect on clinical pain severity and pain-related interference, through sleep disturbance, according to a study published online March 14 in Pain.
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Obesity, Increased Incidence of Rheumatoid Arthritis Linked
TUESDAY, May 1 (HealthDay News) -- Obesity is linked with the risk of developing rheumatoid arthritis (RA), and seems to have contributed to the recent increase in incidence of the condition, according to a study published online April 18 in Arthritis Care & Research.
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Index Identifies Clot Risk in Outpatient Surgery Patients
TUESDAY, May 1 (HealthDay News) -- Using a weighted risk index, the highest-risk outpatient surgery patients have an almost 20-fold increase in risk of venous thromboembolism (VTE) requiring therapy, according to a study published online April 13 in the Annals of Surgery.
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Food Allergy Risk Up for Children Born in the Fall
TUESDAY, May 1 (HealthDay News) -- Children born in the fall have an increased risk of food allergy, with a significantly increased risk seen only for Caucasians and those with eczema, according to a study published online April 19 in Allergy.
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Electronic Records Show Variation in Blood Usage
TUESDAY, May 1 (HealthDay News) -- Electronic information systems can be used to generate detailed information about blood component use by individual providers and surgical services, and they reveal significant variation in utilization, according to research published online April 23 in Anesthesiology.
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Hospital Strategies Linked to Lower Mortality After Acute MI
TUESDAY, May 1 (HealthDay News) -- Five specific hospital performance strategies have been identified that result in lower 30-day risk-standardized mortality rates (RSMRs) for patients with acute myocardial infarction (AMI), according to a study published in the May 1 issue of the Annals of Internal Medicine.
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Caloric Restriction Linked to Reduced Inflammation Markers
TUESDAY, May 1 (HealthDay News) -- Implementation of a caloric restriction weight-loss diet, with or without exercise, is associated with measurable reductions in markers of inflammation for obese or overweight postmenopausal women, according to a study published in the May 1 issue of Cancer Research.
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