Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for December 2006. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Acute Exercise May Help Type 2 Diabetics Control Blood Sugar
FRIDAY, Dec. 29 (HealthDay News) -- Acute bouts of exercise can help patients with insulin-treated type 2 diabetes control their blood sugar levels for at least 24 hours, according to a report in the December issue of Medicine & Science in Sports & Exercise.
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Fruit, Vegetables May Lower Metabolic Syndrome Risk
FRIDAY, Dec. 29 (HealthDay News) -- Eating higher amounts of fruit and vegetables is linked to a lower risk of developing metabolic syndrome. This lower incidence may be due to lower plasma C-reactive protein concentrations, according to the results of an Iranian study published in the December issue of the American Journal of Clinical Nutrition.
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Endometriosis Does Not Appear to Increase Bone Fracture Risk
THURSDAY, Dec. 28 (HealthDay News) -- Although menstrual disorders such as endometriosis have been associated with loss of bone density, women who have the disease are no more likely to sustain fractures than their healthy counterparts, according to a report published in the December issue of Fertility and Sterility.
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Cardiovascular Disease Kills One-Third of Americans
THURSDAY, Dec. 28 (HealthDay News) -- Cardiovascular disease accounted for more than one-third of U.S. deaths in 2004, with prevalence varying by region, according to the American Heart Association's Heart Disease and Stroke Statistics - 2007 Update, published online Dec. 28 in Circulation: Journal of the American Heart Association.
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Insulin Resistance Linked to Platelet Activation
THURSDAY, Dec. 28 (HealthDay News) -- Insulin resistance in obese women is associated with high platelet activation, which can be improved by weight loss or drug treatment to improve insulin sensitivity, researchers report in the Dec. 19 issue of the Journal of the American College of Cardiology.
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Obesity May Cancel Anti-Allergy Effects of Farm Childhood
WEDNESDAY, Dec. 27 (HealthDay News) -- Obesity may reduce the allergy-protective advantages of microbial exposure on farms in early childhood, researchers report in the December issue of the Journal of Allergy and Clinical Immunology.
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Amenorrhea Linked with Abnormal Eating Behavior
TUESDAY, Dec. 26 (HealthDay News) -- Women with functional hypothalamic amenorrhea have higher levels of ghrelin, a hormone linked to feeding behavior, as well as abnormal eating behaviors, but a normal caloric intake, researchers report in the December issue of Fertility and Sterility.
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Skin Autofluorescence Could Signal Type 2 Diabetes Risks
THURSDAY, Dec. 21 (HealthDay News) -- Skin autofluorescence is more common in type 2 diabetics than in non-diabetics, and could be used as a non-invasive way to determine the risk of vascular damage due to diabetes, researchers report in the December issue of Diabetes Care.
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Manipulating Gut Bacteria May Treat Obesity
THURSDAY, Dec. 21 (HealthDay News) -- Obese people have a different composition of gut bacteria than lean people, and a low-fat or low-calorie diet leads to changes in the ratios of these bacteria and weight loss, according to two studies in the Dec. 21/28 issue of Nature.
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Impaired Glucose Disposal Contributes to Pre-Diabetes
WEDNESDAY, Dec. 20 (HealthDay News) -- Postprandial hyperglycemia in early diabetes can be due to an inability to clear glucose rather than due to either increased glucose appearance after a meal or due to an inability to suppress hepatic glucose production, according to the results of a study reported in the December issue of Diabetes.
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HRT May Increase Risk of Impaired Fasting Glucose
WEDNESDAY, Dec. 20 (HealthDay News) -- Female sex hormones play an important role in the pathogenesis of impaired fasting glucose and impaired glucose tolerance and may be the reason sex differences occur for these markers of pre-diabetes, researchers report in the December issue of Diabetes. In addition, postmenopausal women on hormone replacement therapy, or HRT, have a higher risk of impaired fasting glucose than women who are not.
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FDA Issues Updated Alert on Fake Glucose Strips
FRIDAY, Dec. 15 (HealthDay News) -- The U.S. Food and Drug Administration has issued an updated alert on counterfeit glucose strips being sold by pharmacies and stores in the United States. They have included an additional lot number for the strips, which can give patients incorrect blood glucose values.
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Hypoglycemia May Hasten Age-Related Vision Loss
THURSDAY, Dec. 14 (HealthDay News) -- Hypoglycemia can hasten age-related vision loss in mice, according to a report published online Dec. 11 in the Proceedings of the National Academy of Sciences.
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Caloric Restriction-Induced Weight Loss Harms Bones
THURSDAY, Dec. 14 (HealthDay News) -- Men and women who lose weight by reducing their caloric intake may lose bone mineral density, but people who shed pounds by exercising do not, according to the results of a study published in the Dec. 11/25 issue of the Archives of Internal Medicine.
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Fifty Million in U.S. Financially Strained Due to Health Care
TUESDAY, Dec. 12 (HealthDay News) -- Almost 50 million young and middle-aged Americans, or about one in five people, live in families with very high financial burdens because of health care, spending 10 percent or more of their tax-adjusted income on health care services, researchers report in the Dec. 13 issue of the Journal of the American Medical Association.
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Pre-Pregnancy Weight Ups Gestational Diabetes Risk
MONDAY, Dec. 11 (HealthDay News) -- Putting on more excess pounds than expected during pregnancy and obesity significantly increase a woman's gestational diabetes risk, researchers report in the December issue of American Journal of Obstetrics & Gynecology.
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Program Cuts Heart Risk Factors in Medically Underserved
FRIDAY, Dec. 8 (HealthDay News) -- A disease management program for low-income, medically underserved patients has been shown to lower cardiovascular risk factors and retain most study patients during a one-year follow-up, researchers report in the Dec. 1 issue of the American Journal of Cardiology.
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Metformin Helps Curb Weight in Child Psychiatric Patients
THURSDAY, Dec. 7 (HealthDay News) -- Metformin helps young psychiatric patients reverse the weight gain associated with second-generation antipsychotics, researchers report in the December issue of the American Journal of Psychiatry.
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Lipodystrophy Diagnosis Age Linked to Child's Complications
WEDNESDAY, Dec. 6 (HealthDay News) -- Children without HIV who are diagnosed with acquired lipodystrophy at an early age are more likely to experience complications than those diagnosed later on, according to a report in the December issue of the Journal of the American Academy of Dermatology.
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Risk of Late Events Higher with Drug-Eluting Stents
TUESDAY, Dec. 5 (HealthDay News) -- In patients with drug-eluting stents, but not those with bare-metal stents, extended clopidogrel and aspirin use may be needed to reduce the risk of late events such as cardiac death or myocardial infarction, according to two reports published in the Dec. 19 issue of the Journal of the American College of Cardiology and early online Dec. 5 in the Journal of the American Medical Association. An advisory panel to the U.S. Food and Drug Administration is scheduled to review the safety of drug-eluting stents this week.
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'Fat But Fit' Patients Still at Cardiovascular Risk
TUESDAY, Dec. 5 (HealthDay News) -- Overweight patients who have high levels of cardiorespiratory fitness still require weight-loss interventions to improve their cardiovascular risk profiles, according to a study published in the December issue of the American Journal of Cardiology.
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Few Women with Gestational Diabetes Tested After Birth
MONDAY, Dec. 4 (HealthDay News) -- Fewer than half of women with gestational diabetes mellitus get tested for glucose tolerance after giving birth, researchers report in the December issue of Obstetrics & Gynecology.
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Rosiglitazone Shows Modest Benefit for Glycemic Control
MONDAY, Dec. 4 (HealthDay News) -- Rosiglitazone modestly improves glycemic control but may increase the risk of cardiovascular events, edema and weight gain compared with older and cheaper drugs, according to study findings published in the Dec. 7 issue of the New England Journal of Medicine.
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