THURSDAY, May 17 (HealthDay News) -- A new histological staging system for gastritis correlates with status of the gastric mucosa and its prognosis, according to a report published in the May issue of the journal Gut.
Massimo Rugge, M.D., of the University of Padova in Italy, and colleagues applied the Operative Link on Gastritis Assessment (OLGA) histological staging system to 439 dyspeptic patients, to assess the relationship between score, prognosis and cancer risk.
Of 439 patients, 247 had active or eradicated Helicobacter pylori, 34 had peptic ulcers, and seven had some form of neoplasia. The prevalence of H. pylori infection increased with gastritis stage, from 51 percent at stage 0 to 100 percent at stage IV. Duodenal ulcers and other benign conditions consistently clustered in stages 0 to II. Invasive and non-invasive neoplastic lesions clustered in stages III and IV.
"The new OLGA staging system proved easy to use and provided intuitive and clear prognostic and therapeutic information," the authors write. "The OLGA stage should be given as the concluding statement of a 'traditional' histology report or plotted on the 'staging scale' originally proposed by OLGA," they add.
Abstract
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