Here are what the editors at HealthDay consider to be the most important developments in Gastroenterology for September 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
History of Sexual Abuse Slows Response to Bariatric Surgery
FRIDAY, Sept. 28 (HealthDay News) -- Although studies suggest that individuals with a history of sexual abuse may experience less weight loss soon after bariatric surgery, most individuals still benefit from the surgical procedure, with increased weight loss seen over time, according to research published in the October issue of Obesity Reviews.
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Cord Blood-Derived Stem Cells Localize to Intestinal Crypt
WEDNESDAY, Sept. 26 (HealthDay News) -- Cord blood-derived cells can preferentially migrate and engraft into the intestine, which could be useful in treating disorders such as inflammatory bowel disease, according to a study published in the September issue of Hepatology.
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Interrelated Anxiety, GI, and Sensory Issues Common in ASD
TUESDAY, Sept. 25 (HealthDay News) -- For children with autism spectrum disorder (ASD), a possibly interrelated phenomenon of co-existing anxiety, sensory over-responsivity, and gastrointestinal (GI) problems is common, according to a study published online Aug. 1 in the Journal of Abnormal Child Psychology.
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Childhood Antibiotic Exposure Linked to Development of IBD
MONDAY, Sept. 24 (HealthDay News) -- Early exposure to antianaerobic antibiotics in childhood is associated with an increased risk of developing inflammatory bowel disease (IBD), according to research published online Sept. 24 in Pediatrics.
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Linaclotide Relieves Symptoms of IBS With Constipation
THURSDAY, Sept. 20 (HealthDay News) -- Over 26 weeks of treatment, the peptide guanylate cyclase-C agonist linaclotide significantly improves abdominal pain and bowel symptoms in patients with irritable bowel syndrome with constipation (IBS-C), according to research published online Sept. 18 in the American Journal of Gastroenterology.
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Higher Dietary Fructose Tied to Lower Liver Energy Stores
WEDNESDAY, Sept. 19 (HealthDay News) -- Increased dietary fructose consumption may impair hepatocellular energy homeostasis, as seen with reduced levels of liver adenosine triphosphate (ATP), with lower levels seen in those with high uric acid (UA) levels, according to a study published in the September issue of Hepatology.
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Alcohol-Related Esophageal Cancer Risk Is Reversible
WEDNESDAY, Sept. 19 (HealthDay News) -- The alcohol-related effects on esophageal cancer risk are reversible with cessation of alcohol consumption, according to research published in the July issue of Addiction.
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Early Risks, but Better Weight Control With Duodenal Switch
WEDNESDAY, Sept. 19 (HealthDay News) -- For obese patients undergoing bariatric surgery, biliopancreatic diversion/duodenal switch (DS) is less commonly used than gastric bypass (GB), but despite increased early risks, the procedure is associated with better weight and comorbidity control, according to research published online Sept. 17 in the Archives of Surgery.
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Long-Term Benefits of Gastric Bypass Surgery Evaluated
TUESDAY, Sept. 18 (HealthDay News) -- Among obese patients, gastric bypass surgery correlates with higher rates of diabetes remission and lower risk of cardiovascular disease, has little effect on the severity of sleep apnea, and only reduces health care use after the sixth year post-surgery, according to three studies published in the Sept. 19 issue of the Journal of the American Medical Association, a theme issue on obesity.
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Resuming Warfarin After GI Bleed Cuts Mortality
TUESDAY, Sept. 18 (HealthDay News) -- In the 90 days following a gastrointestinal tract bleeding (GIB) event, patients who do not resume warfarin therapy experience an increased rate of thrombosis and death, according to research published online Sept. 17 in the Archives of Internal Medicine.
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Review: Inflammation's Role in Obesity-Colorectal Cancer Link
THURSDAY, Sept. 13 (HealthDay News) -- A new review summarizes the ways in which inflammation and altered metabolism are associated with colorectal cancer in obese individuals; the review was published online Sept. 3 in Obesity Reviews.
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Long-Term Survival High With Living Donor Liver Transplants
MONDAY, Sept. 10 (HealthDay News) -- Patients with acute liver failure (ALF) who receive a living donor liver transplantation (LDLT) in Japan have excellent short- and long-term survival rates, according to a study published in the September issue of Liver Transplantation.
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Not All Docs/Nurses Want to Be Asked About Hand Hygiene
FRIDAY, Sept. 7 (HealthDay News) -- Although most health care workers (HCWs) appreciate the role of patients in preventing health care-associated infection, a considerable proportion are uncomfortable with patients asking about their hand hygiene, according to a letter published online Sept. 3 in the Archives of Internal Medicine.
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Characteristics of Long-Term Gastric Cancer Survivors ID'd
THURSDAY, Sept. 6 (HealthDay News) -- Patients with gastric and gastroesophageal junction (GEJ) cancer who survive for longer than three years after diagnosis seem to have distinct demographic and pathologic characteristics, compared with those who do not survive, according to research published online Sept. 4 in the Journal of Clinical Oncology.
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