TUESDAY, Jan. 30 (HealthDay News) -- Lentigo maligna melanoma are more common in the periocular region than in other body regions, in contrast to other forms of malignant melanoma, according to a review of 29 cases reported in the January issue of Ophthalmology.
Fiona M. Chan, M.B.B.S., of Royal Brisbane Hospital in Brisbane, Australia, and colleagues reviewed charts from 29 patients diagnosed with malignant melanoma localized to the eyelid skin, to collect information on treatment types and outcomes.
The most common location was the lower eyelid, with over half arising in areas of pigmentation. Nineteen cases were typed as lentigo maligna melanoma, while eight others were superficial spreading malignant melanoma. All treatments included wide excision. The authors note that pathologists preferred paraffin sections to frozen sections for melanoma assessment and margin analysis.
The higher frequency of periocular lentigo maligna melanoma may reflect the "cumulative solar damage and an extended radial growth phase in the chronically exposed head and neck region," the authors write. "Margin control by mapped serial excision or a modified Mohs' micrographic surgery using paraffin sections is a useful technique to ensure complete excision and minimization of local recurrence."
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