April 2011 Briefing - Internal Medicine

Here are what the editors at HealthDay consider to be the most important developments in Internal Medicine for April 2011. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Children of Depressed Parents Experience More Stress

FRIDAY, April 29 (HealthDay News) -- Young children respond to stressful situations with higher levels of the stress hormone cortisol when their parents have a history of depression and exhibit negative behavior toward them, according to a study published online April 1 in Psychological Science.

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Bleeding Score Improves Mild Bleeding Disorder Diagnosis

FRIDAY, April 29 (HealthDay News) -- Use of bleeding assessment tools (BATs) improves the evaluation of patients with suspected mild bleeding disorders (MBD), according to a study published online March 21 in the Journal of Thrombosis and Haemostasis.

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Ramipril May Lower End-Stage Renal Disease Risk in Obese

FRIDAY, April 29 (HealthDay News) -- Ramipril may reduce the risk of end-stage renal disease (ESRD) in obese patients with non-diabetic chronic kidney disease (CKD), according to a study published online April 28 in the Journal of the American Society of Nephrology.

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Fractures Seen in Older Levothyroxine Users

FRIDAY, April 29 (HealthDay News) -- Older people who take levothyroxine may be at risk for fractures, particularly if their cumulative doses are medium or high, according to research published online April 28 in BMJ.

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Height and Obesity May Raise Venous Thromboembolism Risk

FRIDAY, April 29 (HealthDay News) -- Tall men may have an increased risk of venous thromboembolism (VTE); whereas tall stature and obesity are associated with an increased VTE risk in both men and women, according to a study published online April 28 in Arteriosclerosis, Thrombosis, and Vascular Biology.

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Increasing Cancer Burden Projected for Ethnic Minorities

THURSDAY, April 28 (HealthDay News) -- Consideration of genetic, ethnic, biologic, and sociological factors is necessary to appropriately diagnose and treat cancer in all U.S. subpopulations, according to the President's Cancer Panel 2009 to 2010 report published April 28.

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Flu Vaccination Safe for Post-Transplant Patients

THURSDAY, April 28 (HealthDay News) -- Influenza vaccination in the first year after renal transplantation is not associated with transplant rejection or loss, according to a study published online April 21 in the Clinical Journal of the American Society of Nephrology.

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CDC: Injuries Cause More Missed Days in Older Workers

THURSDAY, April 28 (HealthDay News) -- While older workers, aged ≥55 years, represented just 17 percent of employer-reported nonfatal occupational injuries and illnesses in 2009, the median number of days older workers spent absent from work exceeded that of younger age groups, according to a report in the April 29 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Infarct Size Varies According to Time of Day

THURSDAY, April 28 (HealthDay News) -- Significant variations in infarct size are associated with circadian oscillations at the time of ST-segment elevation myocardial infarction (STEMI) onset, with the largest infarcts occurring during the dark-to-light transition period (6:00 am to noon), according to a study published online April 27 in Heart.

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Scoliosis Prevalence Increases With Age

THURSDAY, April 28 (HealthDay News) -- The prevalence of scoliosis increases with advancing age, with a higher prevalence in whites, according to a study published in the April 20 issue of Spine.

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Group Care Feasible in Patients With Parkinson's Disease

THURSDAY, April 28 (HealthDay News) -- Group patient visits, in which medical appointments are shared by patients with a common condition, may provide a feasible means of caring for patients with Parkinson's disease, according to research published online April 27 in Neurology.

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Monthly Injection Effective for Opioid Dependence

THURSDAY, April 28 (HealthDay News) -- A once-monthly injection of extended-release naltrexone (XR-NTX) appears to be effective and safe for the treatment of opioid dependence after detoxification, according to a study published online April 28 in The Lancet.

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Leprosy in Southern U.S. May Be a Zoonosis

WEDNESDAY, April 27 (HealthDay News) -- In the Southern United States, wild armadillos and many humans with leprosy are infected with the same strain, and leprosy may be a zoonosis in the region, according to a study published in the April 28 issue of the New England Journal of Medicine.

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Low-Dose Aspirin Affects Post-Surgery Blood Drainage

WEDNESDAY, April 27 (HealthDay News) -- Patients taking low-dose aspirin have significantly increased blood drainage and are at increased risk of complications after spinal surgery, even if they stop taking aspirin seven days before surgery, according to a study published in the April issue of The Spine Journal.

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Lung Problems Common During and After Natural Disasters

WEDNESDAY, April 27 (HealthDay News) -- Pulmonary complications resulting from direct or indirect injury to the lung are a major cause of morbidity and mortality following natural disasters, according to a review published in the April issue of Respirology.

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New Approaches Useful for Management of IBD

WEDNESDAY, April 27 (HealthDay News) -- New therapeutic approaches may be useful in management of inflammatory bowel disease (IBD), specifically for inducing remission and preventing relapse in ulcerative colitis (UC), and Crohn's disease (CD), according to a review published as a supplement to the April issue of The American Journal of Gastroenterology.

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Post-Vietnam-Era Vets Have Highest Substance Use Rate

WEDNESDAY, April 27 (HealthDay News) -- Substance use rates are highest in war veterans who served in the post-Vietnam era (VET), and in those who served in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) in Iraq and Afghanistan and have comorbid diagnoses of bipolar disorder and schizophrenia, according to a study published in the May-June issue of the American Journal on Addictions.

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Student Views of Internal Medicine Have Changed

WEDNESDAY, April 27 (HealthDay News) -- Although medical school students in 2007 were more likely than those in 1990 to view internal medicine (IM) as a potentially meaningful career, the more recent students had higher debt, more negative views of workload and stress in IM, and less interest in general IM as a career, according to a study published in the April 25 issue of the Archives of Internal Medicine.

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Anti-Inflammatory Drugs May Lower Antidepressant Efficacy

WEDNESDAY, April 27 (HealthDay News) -- Anti-inflammatory drugs, including ibuprofen, aspirin, and naproxen, appear to reduce the effectiveness of selective serotonin reuptake inhibitors (SSRIs), according to a study published online April 25 in the Proceedings of the National Academy of Sciences.

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More MI Treatments Tied to Decreased Mortality in Sweden

TUESDAY, April 26 (HealthDay News) -- For patients with ST-elevation myocardial infarction (STEMI) in Sweden, an increase in evidence-based treatments is associated with a decrease in 30-day and one-year mortality, according to a study published in the April 27 issue of the Journal of the American Medical Association.

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Low Health Literacy Tied to Higher Heart Failure Mortality

TUESDAY, April 26 (HealthDay News) -- For outpatients with heart failure, low health literacy is significantly correlated with higher all-cause mortality, according to a study published in the April 27 issue of the Journal of the American Medical Association.

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Health Behavior Interventions Increase Healthy Behaviors

TUESDAY, April 26 (HealthDay News) -- Interventions targeting multiple health-related behaviors are successful at increasing health-related behaviors in HIV-serodiscordant heterosexual African-American couples, according to a study published in the April 25 issue of the Archives of Internal Medicine.

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Black Cancer Patients More Willing to Pay to Extend Life

TUESDAY, April 26 (HealthDay News) -- Black cancer patients are more willing to expend their personal financial resources in order to extend life compared to white cancer patients, according to a study published online April 26 in Cancer.

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ACC/AHA Issue Blood Pressure Control Guidelines for Elderly

TUESDAY, April 26 (HealthDay News) -- The American College of Cardiology (ACC) and the American Heart Association (AHA) have released a consensus document to help clinicians control and reduce the risks for high blood pressure in elderly adults; the document has been published online April 25 in the Journal of the American College of Cardiology.

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Restricted Diet Lowers Triglycerides in Fatty Liver

TUESDAY, April 26 (HealthDay News) -- Restricted intake of carbohydrates or calories for two weeks significantly reduces hepatic triglycerides in individuals with nonalcoholic fatty liver disease (NAFLD), according to a study published in the May issue of The American Journal of Clinical Nutrition.

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Cervical Instabilities Progress in Rheumatoid Arthritis

TUESDAY, April 26 (HealthDay News) -- In patients with rheumatoid arthritis (RA), vertical subluxation (VS) and subaxial subluxation (SAS) increase over time, especially in patients with pre-existing VS, SAS, and/or mutilating changes, according to a study published in the April 15 issue of Spine.

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Diabetes Patients Benefit From Amlodipine Titration

TUESDAY, April 26 (HealthDay News) -- An amlodipine/olmesartan medoxomil (OM)-based titration regimen is well tolerated and may reduce blood pressure (BP) in patients with hypertension and type 2 diabetes, according to a study published in the May 1 issue of The American Journal of Cardiology.

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Those With HIV at Higher Risk for Heart Failure

TUESDAY, April 26 (HealthDay News) -- Individuals with HIV may be at higher risk for heart failure, particularly if they have higher levels of ongoing viral replication, according to research published in the April 25 issue of the Archives of Internal Medicine.

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Mortality Rate in Adults With Hypertension Has Fallen

TUESDAY, April 26 (HealthDay News) -- The all-cause mortality rate among hypertensive adults has dropped in recent decades, but the mortality gap between adults with and without hypertension has remained constant, according to research published in the April 26 issue of Circulation.

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Tai Chi Benefits Heart Failure Patients

TUESDAY, April 26 (HealthDay News) -- Tai chi may improve quality of life, exercise self-efficacy, and mood in people with chronic systolic heart failure, according to research published in the April 26 issue of the Archives of Internal Medicine.

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P. falciparum Infection May Confer Long-Term Protection

MONDAY, April 25 (HealthDay News) -- Artificially induced immunity against infection with Plasmodium falciparum (P. falciparum) may last for 2.5 years or longer, according to a study published online April 25 in The Lancet.

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Raised Death Risk With Low and High Glycated Hemoglobin

MONDAY, April 25 (HealthDay News) -- The relationship between glycated hemoglobin (A1C) and mortality or complications suggests setting a target A1C level higher than 6 percent, and lower than 8 percent in elderly patients with type 2 diabetes, according to a study published online April 19 in Diabetes Care.

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Good Diagnostic Value of Prospective ECG Scans

MONDAY, April 25 (HealthDay News) -- Patients who undergo dual-source computed tomography (DSCT) prospective electrocardiogram (ECG)-triggered protocols have similar scores as those undergoing DSCT retrospective ECG-gated protocols, according to a study published in the May 1 issue of The American Journal of Cardiology.

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Getting Right Amount of Sleep May Help With Weight Loss

MONDAY, April 25 (HealthDay News) -- Sleeping between six and eight hours a night and having less stress may predict an individual's success in a behavioral weight loss intervention, according to a study published online March 29 in the International Journal of Obesity.

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Hypertension Drugs Tied to Risk of Cancer Recurrence

MONDAY, April 25 (HealthDay News) -- Angiotensin-converting enzyme inhibitors (ACEi) appear to be associated with an elevated risk of breast cancer recurrence in women, while beta blockers (BBs) seem to have a protective effect, according to a study published online April 11 in Breast Cancer Research and Treatment.

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Asthma May Increase Risk of Erectile Dysfunction

FRIDAY, April 22 (HealthDay News) -- Asthma may be an independent risk factor for erectile dysfunction (ED), with the risk increasing with asthma severity, according to a study published online March 22 in The Journal of Sexual Medicine.

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Tooth Loss Not Independently Linked to Cognitive Function

FRIDAY, April 22 (HealthDay News) -- Tooth loss due to periodontitis is not independently associated with reduced cognitive function, but may be a marker for poor cognitive function when combined with low socioeconomic status (SES) and advanced age, according to a study published in the April 1 issue of the Journal of the American Dental Association.

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Hemodialysis Vascular Access Type Affects Survival

FRIDAY, April 22 (HealthDay News) -- The reduced survival of patients with end-stage renal disease (ESRD) treated with hemodialysis (HD) rather than peritoneal dialysis (PD) may be associated with administering HD via a central venous catheter (HD-CVC), according to a study published online April 21 in the Journal of the American Society of Nephrology.

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Children and Parents Have Similar Responses to Pain

FRIDAY, April 22 (HealthDay News) -- There is a significant correlation between the way parents and their children respond to pain, according to a study published online March 8 in the International Journal of Behavioral Medicine.

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Cognitive Therapy Found to Reduce Cortical Activation

FRIDAY, April 22 (HealthDay News) -- Cognitive behavioral therapy (CBT) may improve Gilles de la Tourette Syndrome (GTS) symptoms by modifying motor cortical activation, according to a study published in the April issue of the International Journal of Cognitive Therapy.

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Kidney Disease Common in Very Elderly, Tied to CVD

FRIDAY, April 22 (HealthDay News) -- Chronic kidney disease (CKD) appears to be quite prevalent in octogenarians and may be linked with cardiovascular disease (CVD), though different formulas used to assess prevalence provide different results, according to research published online April 21 in the Clinical Journal of the American Society of Nephrology.

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Diabetes Does Not Affect Sexual Dysfunction Prevalence

FRIDAY, April 22 (HealthDay News) -- Sexual dysfunction in women with type 1 diabetes may be predicted by depression symptoms, but the prevalence is similar to that in women without type 1 diabetes, according to a study published online April 7 in The Journal of Sexual Medicine.

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Treatment-Resistant Epilepsy Common in Idiopathic Autism

THURSDAY, April 21 (HealthDay News) -- Treatment-resistant epilepsy (TRE) is relatively common in patients with autism, but surgical resection and vagus nerve stimulator (VNS) implantation offer limited benefit, according to a study published online April 19 in Epilepsia.

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CDC: Half of States Have Smoke-Free Policies

THURSDAY, April 21 (HealthDay News) -- Comprehensive smoke-free policies among U.S. states increased dramatically between 2000 and 2010, making the Healthy People 2020 target of all states having comprehensive smoke-free policies achievable with continued efforts and accelerated efforts in the Southern states, according a report in the April 22 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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It Pays to Screen Immigrants for Tuberculosis

THURSDAY, April 21 (HealthDay News) -- Screening immigrants to the United Kingdom for latent tuberculosis infection based on the incidence in their countries of origin is a cost-effective way of preventing future active cases of tuberculosis, according to a study published online April 21 in The Lancet.

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Three Enterotypes Identified in Human Gut

THURSDAY, April 21 (HealthDay News) -- Three different clusters of microbiota, known as enterotypes, which are not nation or continent specific, have been identified in the gut and may be associated with different human characteristics, according to a study published online April 20 in Nature.

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High BNP Post-CABG Predicts Worse Physical Function

THURSDAY, April 21 (HealthDay News) -- Higher peak postoperative levels of B-type natriuretic peptide (BNP), secreted by the heart in response to stress, are independently associated with worse physical function up to two years after coronary artery bypass graft (CABG) surgery, according to a study published in the April issue of Anesthesiology.

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Intravaginal Probiotic May Lower UTIs in Premenopausal Women

THURSDAY, April 21 (HealthDay News) -- Treatment with an intravaginal suppository probiotic may help prevent recurrent urinary tract infection (UTI) in premenopausal women, according to research published online April 14 in Clinical Infectious Diseases.

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Pioglitazone Not Tied to Most Cancers in Diabetes Patients

THURSDAY, April 21 (HealthDay News) -- Pioglitazone does not appear to be associated with common cancers in people with diabetes, though there may be an increased risk for bladder cancer in those who have received more than two years' treatment with the agent, according to two articles published in the April issue of Diabetes Care.

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Depression After Traumatic Brain Injury Common

THURSDAY, April 21 (HealthDay News) -- About 30 percent of people who suffer traumatic brain injury (TBI) will experience depression, but there is a dearth of evidence to guide the care of the 1.2 million people in the United States who experience TBI each year, according to research published by the Agency for Healthcare Research and Quality.

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Behavioral Interventions Succeed in Promoting Condom Use

THURSDAY, April 21 (HealthDay News) -- Behavioral interventions in young women to promote safer sexual behaviors to protect against transmission of sexually transmitted infections (STIs) may be effective, primarily at encouraging condom use, according to a review published in the Cochrane Database of Systematic Reviews.

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Restricted Life Space Tied to Increased Alzheimer's Risk

THURSDAY, April 21 (HealthDay News) -- Older adults whose life space is restricted to the home environment have a substantially increased risk of Alzheimer's disease (AD), according to a study published online March 22 in the American Journal of Geriatric Psychiatry.

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Researchers Review Risks Tied to Nuclear Accidents

THURSDAY, April 21 (HealthDay News) -- In a new article, researchers review the short- and long-term health risks associated with nuclear power plant accidents in light of the recent earthquake in Japan that caused substantial damage to a nuclear plant. The article has been published online April 20 in the New England Journal of Medicine.

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Polymorphism Linked With Pulmonary Fibrosis

WEDNESDAY, April 20 (HealthDay News) -- Researchers have identified a common variant in the putative promoter of the gene encoding mucin 5B (MUC5B), giving new insight into the pathogenesis of familial interstitial pneumonia and idiopathic pulmonary fibrosis; their findings have been published in the April 21 issue of the New England Journal of Medicine.

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Calcium Supplements Modestly Increase Risk of Heart Attack

WEDNESDAY, April 20 (HealthDay News) -- Use of personal calcium supplements -- with or without vitamin D -- modestly increases the risk of cardiovascular events, especially myocardial infarction (MI), a finding obscured in the Women's Health Initiative Calcium/Vitamin D Supplementation Study (WHI CaD Study), according to an article published online April 19 in BMJ.

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Physical Activity Guidelines May Improve Survival

WEDNESDAY, April 20 (HealthDay News) -- Meeting the recommendations set out in the federal 2008 Physical Activity Guidelines for Americans is associated with reduced all-cause mortality in U.S. adults, according to a study published online April 5 in the American Journal of Preventive Medicine.

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Low-Cost Thromboprophylaxis by Electronic Alerts Effective

WEDNESDAY, April 20 (HealthDay News) -- Electronic alert (e-alert) systems are cost-effective tools for reducing venous thromboembolism (VTE) in hospitalized patients, according to a study published online April 11 in the Journal of Thrombosis and Haemostasis.

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Perioperative MI Common and Usually Asymptomatic

WEDNESDAY, April 20 (HealthDay News) -- Perioperative myocardial infarction (MI) after noncardiac surgery is the most common major vascular complication, with most patients not experiencing ischemic symptoms, according to a study published in the April 19 issue of the Annals of Internal Medicine.

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People With Anosmia Attach Less Importance to Olfaction

WEDNESDAY, April 20 (HealthDay News) -- The importance of smell in the daily life of people with olfactory disorders appears to be less than those with a normal sense of smell, suggesting healthy adaptation to reduced olfactory function, according to research published in the April issue of the Archives of Otolaryngology -- Head & Neck Surgery.

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Off-Label Use of Recombinant Factor VIIa High

WEDNESDAY, April 20 (HealthDay News) -- Off-label use of recombinant factor VIIa (rFVIIa) in the hospital setting greatly exceeds use for approved indications; off-label use does not appear to reduce mortality and may increase the risk for thromboembolism, according to research published in the April 19 issue of the Annals of Internal Medicine.

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Alcohol, Energy Drink Mix Impairs Behavioral Inhibition

TUESDAY, April 19 (HealthDay News) -- Alcohol mixed with energy drinks (AmED) increases self-reported stimulation and impairs behavioral response inhibition compared to alcohol alone, according to a study published online April 19 in Alcoholism: Clinical and Experimental Research.

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New Test Effective for Detection of Tuberculosis

TUESDAY, April 19 (HealthDay News) -- Diagnosis of Mycobacterium tuberculosis (MTB) and rifampicin resistance (RIF), detected by the MTB/RIF test, is accurate and feasible in resource-poor countries, according to a study published online April 19 in The Lancet.

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AHA: Exercise and Dietary Changes Reduce Trigylcerides

TUESDAY, April 19 (HealthDay News) -- Dietary and lifestyle changes that include engaging in regular physical activity, losing excess weight, and replacing saturated dietary fats with healthy unsaturated fats can reduce elevated triglycerides, according to an American Heart Association scientific statement published online April 18 in Circulation.

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Diagnostic Guidelines for Alzheimer's Disease Updated

TUESDAY, April 19 (HealthDay News) -- The National Institute on Aging and the Alzheimer's Association have updated their diagnostic guidelines for Alzheimer's disease for the first time in 27 years; the guidelines have been published online April 19 in Alzheimer's & Dementia: The Journal of the Alzheimer's Association.

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Multiple Sclerosis Variance Linked to UVB Rays, Epstein-Barr

TUESDAY, April 19 (HealthDay News) -- Much of the variance of multiple sclerosis (MS) in England can be explained by exposure to infectious mononucleosis (IM), caused by the Epstein-Barr virus (EBV), and ultraviolet B radiation (UVB), according to a study published in the April 19 issue of Neurology.

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AIDS-Free Survival Affected by CD4 Count at Start of cART

TUESDAY, April 19 (HealthDay News) -- Combined antiretroviral therapy (cART) initiated at a threshold of 0.500 × 109 cells/L may increase the rate of AIDS-free survival compared to initiation at lower thresholds, but does not affect mortality, according to a study published in the April 19 issue of the Annals of Internal Medicine.

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New Biomarker May Improve Acute Kidney Injury Diagnosis

TUESDAY, April 19 (HealthDay News) -- Neutrophil gelatinase-associated lipocalin (NGAL) may be a biomarker for detecting early subclinical acute kidney injury (AKI) and its adverse outcomes in absence of diagnostic increases in serum creatinine, according to a study published in the April 26 issue of the Journal of the American College of Cardiology.

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Maternal Obesity Linked to Neurodevelopmental Disorders

MONDAY, April 18 (HealthDay News) -- Maternal obesity and overweight may be linked to neurodevelopmental problems in offspring in childhood, adolescence, or adulthood, according to a review published online March 17 in Obesity Reviews.

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Injecting Facility Reduces Illicit Drug Use Overdose Deaths

MONDAY, April 18 (HealthDay News) -- A supervised injecting facility (SIF), where drug users can inject pre-obtained illicit drugs, appears to reduce overdose mortality, according to a study published online April 18 in The Lancet.

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Post-Cancer Fatigue Linked to Autonomic Nervous System

MONDAY, April 18 (HealthDay News) -- The long-term fatigue that affects breast cancer survivors may be caused by higher sympathetic and lower parasympathetic activity, according to a study published online March 9 in Psychoneuroendocrinology.

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Left Atrial Distensibility Predicts Heart Attack Outcomes

MONDAY, April 18 (HealthDay News) -- The distensibility of the heart's left atrium (LA) can identify patients with elevated left ventricular filling pressure (LVFP) after an acute myocardial infarction (AMI), and it is a predictor of in-hospital mortality, according to a study published in the April 15 issue of The American Journal of Cardiology.

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Effective Method to Prevent Diabetic Foot Ulcers Lacking

MONDAY, April 18 (HealthDay News) -- Most of the interventions used to prevent diabetic foot ulcers in insensate feet do not show any evidence of benefit, according to a review published in the April issue of Diabetes Care.

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Guidelines Issued for Pituitary Incidentaloma Treatment

MONDAY, April 18 (HealthDay News) -- Treatment options for patients with pituitary incidentaloma should be decided after a complete history, physical examination, and laboratory screening, and, in certain cases, visual examination, according to the new Clinical Practice Guideline (CPG) published in the April issue of the Journal of Clinical Endocrinology & Metabolism.

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Nocturia May Indicate Sleep Apnea in Patients With BPH

FRIDAY, April 15 (HealthDay News) -- Obstructive sleep apnea (OSA) may be the cause of frequent night awakenings and urination in patients with benign prostate enlargement (BPE) reporting nocturia, according to a study published in the March-April issue of the Journal of the American Board of Family Medicine.

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Room for Improvement in Polio Surveillance Observed

FRIDAY, April 15 (HealthDay News) -- Surveillance and reporting standards for polio are below par in many world regions and vary at subnational levels, according to a report published in the April 15 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Stroke Outcomes Similar in Children and Young Adults

FRIDAY, April 15 (HealthDay News) -- Children and young adults who experience acute ischemic stroke tend to have similar stroke severity and clinical outcomes, even though they have different etiology and risk factors, according to a study published online March 21 in the Annals of Neurology.

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U.S. Suicide Rates Rise During Recessions

FRIDAY, April 15 (HealthDay News) -- There appears to be a correlation between U.S. suicide rates and economic recessions, particularly among people in their prime working years, according to research published online April 14 in the American Journal of Public Health.

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Geneva Score Prognostic in Patients Ruled Out for PE

FRIDAY, April 15 (HealthDay News) -- Assessment of clinical probability with a revised Geneva score (RGS) could help predict prognosis in patients for whom pulmonary embolism (PE) has been ruled out, according to research published in the April issue of the Journal of Internal Medicine.

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Statins May Lower Post-Surgery Renal Complications

FRIDAY, April 15 (HealthDay News) -- Patients who use statins before major elective surgery may have a decreased likelihood of post-surgery renal complications and reduced postoperative mortality, according to a study published online April 14 in the Journal of the American Society of Nephrology.

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Neighborhood Social Cohesion May Reduce Stroke Mortality

FRIDAY, April 15 (HealthDay News) -- Social cohesion at the neighborhood level is associated with a protective effect against stroke mortality, especially for whites, according to a study published online April 14 in Stroke.

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Closed Loop System Improves Overnight Glucose Control

FRIDAY, April 15 (HealthDay News) -- In adults with type 1 diabetes, closed loop delivery of insulin (artificial pancreas) appears to improve overnight control of glucose levels and reduce the risk of nocturnal hypoglycemia, according to an article published online April 14 in BMJ.

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Self-Rated Health Predicts Outcomes of Joint Replacement

THURSDAY, April 14 (HealthDay News) -- Mental well-being and self-rated health (SRH) predict outcomes of total joint replacements, more than patients' prior physical health, according to a study published online March 18 in Arthritis Care & Research.

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FDA: Penumbra Coil 400 System Recalled

THURSDAY, April 14 (HealthDay News) -- The U.S. Food and Drug Administration has notified health care providers of a class 1 recall of Penumbra Inc.'s Penumbra Coil 400 system, as a defect may cause premature detachment of the coil, which can lead to serious injury, including blood clots and stroke, due to the coil unintentionally migrating.

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Less Fast Food Eaten After Acute Myocardial Infarction

THURSDAY, April 14 (HealthDay News) -- Patients with acute myocardial infarction (AMI) significantly reduce the amount of fast food they consume six months after AMI, but certain populations still eat fast food on a weekly basis, according to a study published in the April 15 issue of The American Journal of Cardiology.

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Hookah Use Widespread Among College Students

THURSDAY, April 14 (HealthDay News) -- Smoking waterpipe tobacco, or hookah, is an increasingly popular activity among U.S. college students, and tends to be falsely perceived as being safer than cigarette smoking, according to a study published online Feb. 25 in Drug and Alcohol Dependence.

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Breast Cancer Screening Guidelines Confuse Women

THURSDAY, April 14 (HealthDay News) -- The new recommendations on breast cancer screening released by the U.S. Preventive Services Task Force confuse women more than they help them understand when to get a mammogram, according to a study published online April 5 in the American Journal of Preventive Medicine.

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Ecstasy May Reduce Hippocampal Volume

THURSDAY, April 14 (HealthDay News) -- Ecstasy (3, 4-methylenedioxymethamphetamine) users have a reduced hippocampal volume, which may explain their memory deficits, according to a study published online March 28 in the Journal of Neurology, Neurosurgery & Psychiatry.

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Atrophy in AD-Related Areas Tied to Disease Development

THURSDAY, April 14 (HealthDay News) -- Researchers have found a correlation between atrophy in Alzheimer's disease (AD)-related brain areas and subsequent AD, which also appears to be influenced by vascular risk factors (VRF), according to two articles published online April 13 in Neurology.

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Incidence of and Hospitalization for Dengue Fever Escalate

THURSDAY, April 14 (HealthDay News) -- The incidence of and hospitalization for dengue fever increased significantly from 2000 to 2007, according to a study published online April 13 in Emerging Infectious Diseases.

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MRSA Prevention Programs Have Conflicting Results

WEDNESDAY, April 13 (HealthDay News) -- A program involving intensive efforts to prevent the incidence and spread of methicillin-resistant Staphylococcus aureus (MRSA) infections in health care facilities does not appear to be effective, though another program involving the same types of efforts does seem to be, according to two studies with conflicting findings published in the April 14 issue of the New England Journal of Medicine.

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More Than Half of U.S. Adults Take Dietary Supplements

WEDNESDAY, April 13 (HealthDay News) -- Adult U.S. dietary supplement intake has increased since 1988-1994, according to a National Center for Health Statistics (NCHS) data brief published April 13 by the U.S. Centers for Disease Control and Prevention.

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Nasal Insulin Induces Immune Tolerance of Injected Insulin

WEDNESDAY, April 13 (HealthDay News) -- Nasal insulin does not affect β-cell function, but does induce immune tolerance to insulin, according to a study published in the April issue of Diabetes.

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Epilepsy May Increase the Risk of Cerebral Tumors

WEDNESDAY, April 13 (HealthDay News) -- Individuals who have new-onset epilepsy have an increased risk for developing cerebral tumors, according to a study published online March 28 in the Journal of Neurology, Neurosurgery & Psychiatry.

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Central Hair Loss Prevalent in African-American Women

WEDNESDAY, April 13 (HealthDay News) -- Central centrifugal cicatricial alopecia (CCCA) appears to be highly prevalent in African-American women, and may be associated with type 2 diabetes, bacterial scalp infections, and hairstyles associated with traction, according to research published in the April issue of the Archives of Dermatology.

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Antibiotics for Acne May Not Up Prevalence of S. aureus

WEDNESDAY, April 13 (HealthDay News) -- Contrary to common ideology, use of long-term tetracycline antibiotics for acne treatment does not appear to increase the prevalence of Staphylococcus aureus (S. aureus) or resistance to the antibiotics, according to research published online April 11 in the Archives of Dermatology.

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Adalimumab Antibodies Linked to Treatment Failure

WEDNESDAY, April 13 (HealthDay News) -- Development of antibodies against adalimumab may have an effect on treatment discontinuation, disease activity, and remission in patients with rheumatoid arthritis (RA), according to a study published April 13 in an infectious disease and immunology themed issue of the Journal of the American Medical Association.

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Vitamin D Levels May Reduce Risk of Macular Degeneration

WEDNESDAY, April 13 (HealthDay News) -- Serum 25-hydroxyvitamin D (25[OH]D) concentrations may be associated with a reduced likelihood of developing early age-related macular degeneration (AMD) in women younger than 75 years, according to a study published in the April issue of the Archives of Ophthalmology.

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Non-AIDS-Defining Cancers Increase Among HIV Patients

WEDNESDAY, April 13 (HealthDay News) -- In the last 15 years, there has been a large increase in the number of non-AIDS-defining cancers among HIV-infected individuals, according to a study published online April 11 in the Journal of the National Cancer Institute.

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Fixed-Dose Combos Equally Effective in TB Treatment

TUESDAY, April 12 (HealthDay News) -- Compared with separately administered drugs, a four-drug fixed-dose combination (FDC) regimen partially satisfies noninferiority criteria for tuberculosis treatment, according to a study published April 13 in an infectious disease and immunology themed issue of the Journal of the American Medical Association.

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Increased Genital Shedding in Symptomatic HSV-2 Patients

TUESDAY, April 12 (HealthDay News) -- Genital shedding of herpes simplex virus type 2 (HSV-2) is less frequent in individuals with asymptomatic infection who also have less frequent genital lesions, according to a study published April 13 in an infectious disease and immunology themed issue of the Journal of the American Medical Association.

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Rheumatoid Arthritis Treatment May Reduce Diabetes Risk

MONDAY, April 11 (HealthDay News) -- Extended use of tumor necrosis factor α (TNFα) antagonists in patients with rheumatoid arthritis (RA) may reduce the risk of developing insulin resistance (IR), according to a review published in the April issue of Arthritis Care & Research.

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Glucose Variability Has No Cardio Protective Role

TUESDAY, April 12 (HealthDay News) -- Reduction in intraday glucose variability (GV) in treatment of patients with type 2 diabetes does not affect subsequent secondary cardiovascular events, according to a study published in the April issue of Diabetes Care.

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End-of-Life Care for Medicare Patients Changing

TUESDAY, April 12 (HealthDay News) -- Care for chronically ill Medicare patients at end-of-life changed between 2003 and 2007, with patients spending less time in the hospital and more time in hospice care, and care also grew more intense during that five-year period, according to a new Dartmouth Atlas Project report.

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Substantial Weight Loss With Phentermine and Topiramate

TUESDAY, April 12 (HealthDay News) -- Overweight and obese individuals treated with phentermine and topiramate achieve substantial dose-related weight loss, according to a study published online April 11 in The Lancet.

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Memantine Not Indicated in Mild Alzheimer's Disease

TUESDAY, April 12 (HealthDay News) -- Memantine provides no treatment benefit in mild Alzheimer's disease (AD) and has only limited efficacy in moderate AD, according to a meta-analysis published online April 11 in the Archives of Neurology.

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Physicians Choose Low Death Risk Treatment for Patients

TUESDAY, April 12 (HealthDay News) -- Physicians recommend low mortality risk treatment with more adverse effects for their patients but opt for higher mortality risk treatment with less adverse effects for themselves in a similar scenario, according to a study published in the April 11 issue of the Archives of Internal Medicine.

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Future-Directed Therapy a New Option to Treat Depression

TUESDAY, April 12 (HealthDay News) -- Future-directed therapy (FDT), a novel form of therapy for major depressive disorder (MDD) that teaches skills to help individuals focus on a more positive future, may be an effective treatment option for patients with depression, according to a study published online March 16 in CNS Neuroscience & Therapeutics.

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Better Models Predict Kidney Disease Progression

MONDAY, April 11 (HealthDay News) -- A model incorporating routine laboratory tests appears accurate in predicting progression to kidney failure in patients with chronic kidney disease (CKD), and combining three markers of kidney disease better classifies patients at risk of end-stage kidney disease and death, according to two articles published online April 11 in the Journal of the American Medical Association to coincide with presentation at the World Congress of Nephrology, held from April 8 to 12 in Vancouver, Canada.

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Neurocognitive Impairment Up in Childhood Cancer Survivors

MONDAY, April 11 (HealthDay News) -- Survivors of childhood cancer may be at risk of neurocognitive impairment associated with fatigue and sleep disorders, according to a study published online April 11 in Cancer.

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First U.S. Test to Diagnose Dengue Fever Approved

MONDAY, April 11 (HealthDay News) -- The first test to help diagnose people with symptoms of the mosquito-borne virus dengue fever has been approved by the U.S. Food and Drug Administration.

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Negative Health Behaviors Identified in Young Parents

MONDAY, April 11 (HealthDay News) -- Parents of young children have lower physical activity levels compared to young adults of the same age without children, and mothers have poorer dietary intake and higher body mass index (BMI) compared to women without children, according to a study published online April 11 in Pediatrics.

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Dairy Products Tied to Lower Metabolic Syndrome Incidence

MONDAY, April 11 (HealthDay News) -- High consumption of dairy products (other than cheese) and calcium is associated with a lower nine-year incidence of metabolic syndrome (MetS) and impaired fasting glycemia and/or type 2 diabetes (IFG/T2D), according to a study published in the April issue of Diabetes Care.

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Smoking After Cancer Diagnosis Worsens Quality of Life

MONDAY, April 11 (HealthDay News) -- Caregiver mental quality of life (QoL) is worse in lung and colorectal patient-caregiver dyads in which one member of the dyad smokes, according to a study published in the February issue of Cancer Epidemiology, Biomarkers & Prevention.

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Imatinib Reduces Cutaneous Systemic Sclerosis Symptoms

MONDAY, April 11 (HealthDay News) -- Imatinib mesylate is well tolerated by patients with diffuse cutaneous systemic sclerosis (dcSSc) with improvement in skin thickening and forced vital capacity (FVC), according to a study published online March 11 in the Annals of the Rheumatic Diseases.

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Bipolar Sealer Not Preferable to Electrocautery in Arthroplasty

FRIDAY, April 8 (HealthDay News) -- Use of a bipolar sealer to achieve hemostasis during uncomplicated primary total hip arthroplasty does not appear to have any advantages over standard electrocautery, according to research published in the March 16 issue of The Journal of Bone & Joint Surgery.

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FDA OKs Rapid Test to Spot C. difficile Infection

FRIDAY, April 8 (HealthDay News) -- A test designed to rapidly detect the genetic fingerprint of Clostridium difficile bacterial infection has been approved by the U.S. Food and Drug Administration.

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Telaprevir Increases Second-Phase Hepatitis C Decline

FRIDAY, April 8 (HealthDay News) -- Analysis of the kinetics of telaprevir treatment for hepatitis C virus (HCV) shows a rapid second-phase viral decline, which may allow for shorter duration of treatment, according to a study published online March 7 in Hepatology.

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Erectile Dysfunction Tied to Cardiovascular Death Risk

FRIDAY, April 8 (HealthDay News) -- The risk of mortality due to cardiovascular causes increases in men with erectile dysfunction (ED); however, in the first five years after ED manifestation, there is a higher proportion of deaths due to oncological causes, according to a study published online March 22 in The Journal of Sexual Medicine.

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Nonalcoholic Fatty Liver Disease Tied to Higher CRC Risk

FRIDAY, April 8 (HealthDay News) -- Patients with nonalcoholic fatty liver disease (NAFLD) undergoing screening colonoscopy have more early or precursor colorectal carcinoma (CRC) lesions compared to subjects without NAFLD, according to a study published online March 17 in the Journal of Internal Medicine.

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Meditation Affects Brain Activation to Reduce Pain

FRIDAY, April 8 (HealthDay News) -- Meditation significantly reduces both pain intensity and unpleasantness, and the pain relief is associated with alterations in brain regions related to cognitive modulation of pain, according to a study published in the April 6 issue of The Journal of Neuroscience.

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Independent Circadian Blood Pressure Rhythm Identified

FRIDAY, April 8 (HealthDay News) -- The human body has an independent circadian rhythm of blood pressure (BP), which peaks around 9 p.m., according to a study published online April 7 in the Circulation Research.

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Virtual Reality Improves Stroke Patients' Motor Skills

FRIDAY, April 8 (HealthDay News) -- Virtual reality (VR) technology can assist in arm motor recovery after stroke, according to a meta-analysis published online April 7 in Stroke.

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Alcohol Consumption Linked to Higher Cancer Incidence

FRIDAY, April 8 (HealthDay News) -- A substantial number of cancer cases in both men and women can be attributed to alcohol consumption, according to a study published online April 7 in the BMJ.

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Imported Measles Cases in 2011 on Par With Recent Years

THURSDAY, April 7 (HealthDay News) -- The total number of reported measles cases in the United States in the first two months of 2011 appears to be comparable to the number of reported cases each year between 2001 and 2010, according a report in the April 8 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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'Global Trigger Tool' Identifies 10 Times More Errors

THURSDAY, April 7 (HealthDay News) -- Use of the new Global Trigger Tool, developed by the Institute for Healthcare Improvement, detects at least 10 times more adverse events than other methods currently in use, according to a study published in the April issue of Health Affairs.

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Horizant Approved to Treat Restless Legs Syndrome

THURSDAY, April 7 (HealthDay News) -- Horizant extended release tablets (gabapentin enacarbil) have been approved as a once-daily treatment for restless legs syndrome (RLS).

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Partner Violence Victims Not Identified in Emergency Room

THURSDAY, April 7 (HealthDay News) -- Although most victims of intimate partner violence (IPV) present to the emergency department (ED), they are not usually identified and may not receive interventions, according to a study published online March 15 in the Journal of General Internal Medicine.

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Electronic Systems Reduce Drug Errors in Psychiatry

THURSDAY, April 7 (HealthDay News) -- The combination of an electronic prescribing system and a computerized error reporting system significantly reduces the number of medication errors in a hospital's psychiatric unit, according to a study published in the March issue of the Journal of Psychiatric Practice.

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Self-Management of Anticoagulant Therapy Effective

THURSDAY, April 7 (HealthDay News) -- Patient self-testing (PST), alone or in combination with patient self-management (PSM) of anticoagulant doses, reduces thromboembolic complications and all-cause mortality without increasing major bleeding events, according to a meta-analysis published in the April 5 issue of the Annals of Internal Medicine.

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New Yellow Fever Vaccine Safe and Effective

THURSDAY, April 7 (HealthDay News) -- A new vaccine against yellow fever that contains inactivated yellow fever antigen shows promise as a safe alternative to live vaccine, according to research published in the April 7 issue of the New England Journal of Medicine.

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Adolescent BMI May Predict Later Obesity-Related Disease

WEDNESDAY, April 6 (HealthDay News) -- An elevated body mass index (BMI) at age 17, even one within what is considered normal, may be predictive of coronary heart disease in adulthood, according to research published in the April 7 issue of the New England Journal of Medicine.

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Respiratory Distress Syndrome Tied to Long-Term Problems

WEDNESDAY, April 6 (HealthDay News) -- People who experience acute respiratory distress syndrome (ARDS) may feel the ramifications long after discharge in terms of physical limitations, psychological problems, and incurred costs, according to research published in the April 7 issue of the New England Journal of Medicine.

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Reduced Mortality in Very Elderly Heart Failure Patients

WEDNESDAY, April 6 (HealthDay News) -- In the last decade, mortality for elderly heart failure patients has improved, but readmission to the hospital still occurs frequently, according to a study published online April 5 in Circulation: Heart Failure.

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Migration May Spur Depression, Anxiety Disorders

WEDNESDAY, April 6 (HealthDay News) -- Mexicans who migrate to the United States appear to be at higher risk for depressive and anxiety disorders than their family members who stay in Mexico, though this association is seen only in younger birth cohorts, according to research published in the April issue of the Archives of General Psychiatry.

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Being Poor Associated With Higher Risk of Mental Disorders

WEDNESDAY, April 6 (HealthDay News) -- People from low-income households may be at increased risk of mental disorders, and a decrease in household income is linked to an increased risk for incident mental disorders, according to a study published in the April issue of the Archives of General Psychiatry.

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Non-Communicable Diseases Present a Global Health Crisis

WEDNESDAY, April 6 (HealthDay News) -- The global burden of non-communicable diseases (NCDs) is increasing, and a global movement is needed to tackle them, according to a report published online April 6 in The Lancet.

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Maximum Daily Opioid Doses Increase Mortality Risk

TUESDAY, April 5 (HealthDay News) -- Patients prescribed higher daily opioid doses for pain are at increased risk of opioid overdose death, according to a study published in the April 6 issue of the Journal of the American Medical Association.

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Alteration in Health Outcomes Post Estrogen Therapy

TUESDAY, April 5 (HealthDay News) -- Among postmenopausal women with prior hysterectomy, cessation of conjugated equine estrogen (CEE) therapy reduces the risk of stroke, and the risk of breast cancer remains reduced, according to a study to be published on April 6 in the Journal of the American Medical Association.

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Sudden Death Among Athletes Higher Than Formerly Reported

TUESDAY, April 5 (HealthDay News) -- The incidence of sudden cardiac death (SCD) in National Collegiate Athletic Association (NCAA) student-athletes is higher than previous estimates suggest, with a rate of one in 43,770 athletes suffering SCD, according to a study published online April 4 in Circulation.

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Working Long Hours May Predict Risk of Heart Disease

TUESDAY, April 5 (HealthDay News) -- Working long hours may increase the risk of coronary heart disease (CHD), and information on working hours can improve CHD prediction in a low-risk, employed population, according to a study published in the April 5 issue of the Annals of Internal Medicine.

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Four New Alzheimer's Disease Genes Identified

MONDAY, April 4 (HealthDay News) -- Researchers have identified four new genes linked to Alzheimer's disease that individually appear to add to the risk of developing the disease; their findings have been published online April 3 in Nature Genetics.

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Rituximab Does Not Improve Safety Profile of RA Treatment

MONDAY, April 4 (HealthDay News) -- Combining rituximab with a tumor necrosis factor (TNF) inhibitor and methotrexate (MTX) in patients with rheumatoid arthritis (RA) does not offer any safety improvement, according to a study published in the March issue of Arthritis & Rheumatism.

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Patients, Doctors Agree OA Care Needs Improvement

MONDAY, April 4 (HealthDay News) -- Patients with osteoarthritis (OA) and health professionals involved in treatment agree about health care provision for OA, stressing the need for an OA specialist in primary care and better information at or soon after diagnosis, according to a study published online March 8 in Arthritis Care & Research.

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Community-Associated MRSA Infections Are Seasonal

MONDAY, April 4 (HealthDay News) -- During the summer and autumn months, community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections peak in all ages; whereas hospital-associated MRSA (HA-MRSA) peaks are seen in pediatric patients only, according to a study published March 23 in PLoS ONE.

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Rapid Tuberculosis Diagnostic Methods Inaccurate Alone

MONDAY, April 4 (HealthDay News) -- Rapid microbial and immunological diagnostic methods are not accurate enough to diagnose or exclude pulmonary tuberculosis, according to a study published online March 21 in the Journal of Internal Medicine.

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Breast Cancer Survival Factors for Underserved Identified

MONDAY, April 4 (HealthDay News) -- Advanced stages at presentation, and limited diagnostic and treatment capabilities, contribute to lower breast cancer survival in low-income and middle-income countries (LMC), according to the executive summary of the Breast Health Global Initiative Consensus 2010, published in the April issue of The Lancet Oncology.

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Prostate Cancer Screening May Not Reduce Mortality

FRIDAY, April 1 (HealthDay News) -- Screening for prostate cancer may not reduce prostate cancer-specific mortality, according to research published online March 31 in BMJ.

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College Students Wrongly Think Their Hearing Is Normal

FRIDAY, April 1 (HealthDay News) -- College students who believe they have normal hearing may have some degree of hearing loss, according to a study published in the March issue of the International Journal of Audiology.

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Total Hip Arthroplasty Treats Developmental Hip Dysplasia

FRIDAY, April 1 (HealthDay News) -- Cementless modular total hip arthroplasty together with subtrochanteric osteotomy appears to be a satisfactory treatment for patients with prior Crowe Group-IV dysplasia of the hip, according to research published in the March 16 issue of The Journal of Bone & Joint Surgery.

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Low Nutrients Tied to Anemia Risk in Postmenopausal Women

FRIDAY, April 1 (HealthDay News) -- Inadequate nutrient intake is associated with greater risk for anemia in postmenopausal women, according to a study published in the April issue of the Journal of the American Dietetic Association.

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Effects of Statin Therapy Independent of KIF6 Genotype

FRIDAY, April 1 (HealthDay News) -- Statin therapy significantly reduces the incidence of coronary and other major vascular events irrespective of the KIF6 Trp719Arg polymorphism (rs20455) genotype, according to a study published online March 30 in the Journal of the American College of Cardiology.

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Cancer Rates, Cancer Mortality Rates Falling in U.S.

FRIDAY, April 1 (HealthDay News) -- Newly diagnosed cancer rates and cancer-related mortality rates in the United States are steadily declining, according to the "Annual Report to the Nation on the Status of Cancer," published online March 31 in the Journal of the National Cancer Institute.

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Medication, Communication Alleviate Latino Depression

FRIDAY, April 1 (HealthDay News) -- Among Latinos, symptoms of depression are more likely to abate with the use of antidepressants and quality doctor-patient communication, but symptoms are more likely to persist in the presence of stigma toward antidepressants, according to a study published online Jan. 19 in General Hospital Psychiatry.

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Similar Graft Survival for Recipients of Older Kidneys

FRIDAY, April 1 (HealthDay News) -- Total graft survival during a four-year follow-up period is comparable for recipients of kidneys from older (age 60 years or older) donors, younger donors, or from deceased standard criteria donors (SCDs), according to a study published online March 14 in the American Journal of Transplantation.

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Autoimmune Diseases Number Two Cause of Chronic Illness

FRIDAY, April 1 (HealthDay News) -- Autoimmune diseases are the second leading cause of chronic illness in the United States and constitute a major direct and indirect economic burden to the U.S. health care system, according to a report released by the American Autoimmune Related Diseases Association (AARDA) on March 22 at a congressional briefing.

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Cell Phone Proximity to Hip Tied to Bone Mineralization

FRIDAY, April 1 (HealthDay News) -- Men who carry their cell phone next to their hip may have reduced bone mineral content (BMC) and bone mineral density (BMD) in same side hip, according to a study published in the March issue of the Journal of Craniofacial Surgery.

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MRI Found to Improve Breast Cancer Detection Rate

FRIDAY, April 1 (HealthDay News) -- Using a combination of magnetic resonance (MR) imaging and mammography increases sensitivity of cancer detection in women with a history of chest irradiation compared to using either modality on its own, according to a study published in the April issue of Radiology.

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Lower Exercise Tolerance in Patients With Turner Syndrome

FRIDAY, April 1 (HealthDay News) -- Women with Turner syndrome (TS) have lower maximal aerobic capacity and lower exercise tolerance than controls, according to a study published in the April 1 issue of The American Journal of Cardiology.

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