July 2011 Briefing - Rheumatology

Here are what the editors at HealthDay consider to be the most important developments in Rheumatology for July 2011. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Increase in Gout Prevalence From 1988 to 2008

THURSDAY, July 28 (HealthDay News) -- The prevalence of gout and hyperuricemia in the United States is considerable and has increased over the past two decades, according to a study published online July 28 in Arthritis & Rheumatism.

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Quinacrine + Hydroxychloroquine Effective in Cutaneous Lupus

THURSDAY, July 21 (HealthDay News) -- Patients with cutaneous lupus erythematosus (CLE) who fail to respond to hydroxychloroquine alone may respond to the addition of quinacrine, but may also benefit from continuation of hydroxychloroquine monotherapy despite initial lack of response, according to a study published online July 18 in the Archives of Dermatology.

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BMI Changes Predictive of Bilateral Knee Pain in Women

FRIDAY, July 15 (HealthDay News) -- Changes in body mass index (BMI) are associated with year 15 (Y15) bilateral knee pain in women irrespective of radiographic knee osteoarthritis (RKOA) status, according to a study published online July 7 in Arthritis Care & Research.

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Low Bone Mass Seen Early in Multiple Sclerosis

THURSDAY, July 14 (HealthDay News) -- Newly diagnosed patients with multiple sclerosis (MS) with no or minor physical disability seem to have low bone mass, according to a study published in the July 12 issue of Neurology.

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Overweight, Exercise Tied to Increased Joint Replacement Risk

TUESDAY, July 12 (HealthDay News) -- Men who are overweight and engage in vigorous exercise have an increased risk of undergoing total joint replacement (TJR), according to a study published online July 11 in Arthritis & Rheumatism.

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Vitamin D Insufficiency Prevalent in Psoriatic Arthritis

MONDAY, July 11 (HealthDay News) -- Patients with psoriatic arthritis (PsA) have a high prevalence of vitamin D insufficiency, with no evidence of seasonal or geographic variation or association between vitamin D levels and disease activity, according to a study published online July 11 in Arthritis Care & Research.

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Genes in Wnt-Signaling Pathway Tied to Dupuytren's Disease

THURSDAY, July 7 (HealthDay News) -- Nine different gene loci are associated with Dupuytren's disease, six of which are involved in the Wnt-signaling pathway, according to a study published online July 6 in the New England Journal of Medicine.

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Higher Incidence of OA Seen in U.S. Military

THURSDAY, July 7 (HealthDay News) -- Active duty U.S. military personnel have significantly higher incidence rates (IRs) for osteoarthritis (OA) than comparable age groups in the general population, according to a study published online June 29 in Arthritis & Rheumatism.

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