FRIDAY, July 11, 2025 (HealthDay News) -- Consistently and increasingly accumulated physical activity (PA) is associated with a reduced risk for all-cause and cardiovascular disease (CVD) mortality, according to a review published online July 10 in the British Journal of Sports Medicine.Ruyi Yu, from the University of Queensland in Brisbane, Australia, and colleagues conducted a systematic review and meta-analysis to examine the associations of trajectories and accumulation of PA over adulthood with all-cause, CVD, and cancer mortality. A total of 85 studies with three main types of PA exposure were included: 77, 34, and 15 studies assessed all-cause, CVD, and cancer mortality, respectively.The researchers observed an association for higher PA with lower risks for all outcomes. Consistently and increasingly active individuals had lower risks for all-cause and CVD mortality by around 20 to 40 percent and 30 to 40 percent, respectively; the associations with decreasing PA patterns were less evident. Similar inverse associations were seen between higher PA levels and all-cause and CVD mortality with time-varying and cumulative/average PA. For cancer mortality, the associations were found to be weaker and less robust. Risk reductions in all-cause and CVD mortality were suggested for meeting PA guidelines in nonlinear dose-response associations, but even below the guidelines, consistent/increasing PA provided health benefits."By capturing these patterns, this review may provide valuable insights for future research and public interventions aiming at promoting sustained PA in adults," the authors write.Abstract/Full Text.Sign up for our weekly HealthDay newsletter